Cirrhosis causes a heavy global burden. In this review, we summarized up-to-date
epidemiological features of cirrhosis and its complications. Recent epidemiological studies …

Humans harbour large quantities of microbes, including bacteria, fungi, viruses and
archaea, in the gut. Patients with liver disease exhibit changes in the intestinal microbiota …

Acute-on-chronic liver failure (ACLF), which was described relatively recently (2013), is a
severe form of acutely decompensated cirrhosis characterised by the existence of organ …

Background & Aims Bacterial infections in cirrhosis are associated with increased bleeding
risk. To assess the factors responsible for bleeding tendency in patients with bacterial …

Strategies to prevent infection and improve outcomes in patients with cirrhosis. HAV,
hepatitis A virus; HBV, hepatitis B virus; COVID-19, novel coronavirus disease 2019; NSBB …

Inflammation-associated diseases encompass a range of infectious diseases and non-
infectious inflammatory diseases, which continuously pose one of the most serious threats to …

Non-alcoholic fatty liver disease (NAFLD) is currently the most prevalent cause of chronic
liver disease (CLD). Currently, the only therapeutic recommendation available is a lifestyle …

Cirrhosis is the common end-stage of chronic liver diseases of different etiology. The altered
bile acids metabolism in the cirrhotic liver and the increase in the blood-brain barrier …

Acute-on-chronic liver failure (ACLF) is the most severe form of acutely decompensated
cirrhosis and is characterized by the presence of one or more organ failures, intense …

Liver disease, a major cause of global mortality, has been associated with dysbiosis of the
intestinal microbiota (bacteria, fungi, viruses, and other microbes). Studies have associated …