Bioactive signaling lipids as drivers of chronic liver diseases
Lipids are important components for multiple cellular functions, and most have structural or
energy storage roles. However, a small fraction of lipids exerts bioactive roles through …
energy storage roles. However, a small fraction of lipids exerts bioactive roles through …
[HTML][HTML] Cardio-oncology: Shared genetic, metabolic, and pharmacologic mechanism
Y Zhao, H Jia, X Hua, T An, J Song - Current Cardiology Reports, 2023 - Springer
Abstract Purpose of Review The article aims to investigate the complex relationship between
cancer and cardiovascular disease (CVD), with a focus on the effects of cancer treatment on …
cancer and cardiovascular disease (CVD), with a focus on the effects of cancer treatment on …
[HTML][HTML] Study on the molecular mechanism of anti-liver cancer effect of Evodiae fructus by network pharmacology and QSAR model
PY Chen, LT Han - Frontiers in Chemistry, 2023 - frontiersin.org
Introduction: Evodiae Fructus (EF) is the dried, near ripe fruit of Euodia rutaecarpa (Juss.)
Benth in Rutaceae. Numerous studies have demonstrated its anti-liver cancer properties …
Benth in Rutaceae. Numerous studies have demonstrated its anti-liver cancer properties …
[HTML][HTML] Obesity contributes to hepatocellular carcinoma development via immunosuppressive microenvironment remodeling
J Yang, J He, Y Feng, M Xiang - Frontiers in Immunology, 2023 - frontiersin.org
It is generally recognized that the initiation of obesity-related hepatocellular carcinoma
(HCC) is closely associated with hepatic inflammation. However, the paradoxical role of …
(HCC) is closely associated with hepatic inflammation. However, the paradoxical role of …
Exploring the molecular mechanism of berberine for treating diabetic nephropathy based on network pharmacology
L Yang, S Yuan, R Wang, X Guo, Y Xie, W Wei… - International …, 2024 - Elsevier
Background and purpose Diabetic nephropathy (DN) is a prevalent complication of diabetes
mellitus characterized by hyperglycemia, hyperlipidemia, albuminuria and edema …
mellitus characterized by hyperglycemia, hyperlipidemia, albuminuria and edema …
[HTML][HTML] The Emerging Role of LPA as an Oncometabolite
T Karalis, G Poulogiannis - Cells, 2024 - mdpi.com
Lysophosphatidic acid (LPA) is a phospholipid that displays potent signalling activities that
are regulated in both an autocrine and paracrine manner. It can be found both extra-and …
are regulated in both an autocrine and paracrine manner. It can be found both extra-and …
The Potential of the Nutraceutical Berberine in the Treatment of Hepatocellular Carcinoma and other Liver Diseases such as NAFLD and NASH.
M Cervello, G Augello, L Cocco, S Ratti… - Advances in Biological …, 2024 - Elsevier
Hepatocellular carcinoma (HCC) is a common cancer which unfortunately has poor
outcomes. Common anti-cancer treatments such as chemotherapy and targeted therapy …
outcomes. Common anti-cancer treatments such as chemotherapy and targeted therapy …
LPAR6 Participates in Neuropathic Pain by Mediating Astrocyte Cells via ROCK2/NF-κB Signal Pathway
X Fan, R Chu, X Jiang, P Ma, Y Chu, T Hua… - Molecular …, 2024 - Springer
Neuropathic pain (NPP) is a common type of chronic pain. Glial cells, including astrocytes
(AS), are believed to play an important role in the progression of NPP. AS cells can be …
(AS), are believed to play an important role in the progression of NPP. AS cells can be …
[引用][C] Neg-Entropy Mechanism as a Target for Natural Medicines
TL Gao, HH Guo, JD Jiang - Engineering, 2024 - Elsevier