Mechanism of specific tumor-cell lysis by alloimmune T lymphocytes: resolution and characterization of discrete steps in the cellular interaction
E Martz - Contemporary Topics in Immunobiology: T Cells, 1977 - Springer
A cytolytic thymus-derived lymphocyte (CTL)* is a specialized cell the recognized function of
which is immune killing. CTLs are generated by a process of antigen-induced clonal …
which is immune killing. CTLs are generated by a process of antigen-induced clonal …
Cytolytic T lymphocytes
M Nabholz, HR MacDonald - Annual review of immunology, 1983 - annualreviews.org
Cytolytic T Lymphocytes Page 1 Ann. Rev. ImmunoL 1983. 1:273-306 Copyright й 1983 by
Annual Reviews Inc. All rights reserved CYTOLYTIC T LYMPHOCYTES M Nabholz Genetics …
Annual Reviews Inc. All rights reserved CYTOLYTIC T LYMPHOCYTES M Nabholz Genetics …
Generation of cytotoxic T lymphocytes in vitro: I. Response of normal and immune mouse spleen cells in mixed leukocyte cultures
JC Cerottini, HD Engers, HR MacDonald… - The Journal of …, 1974 - rupress.org
Mouse cytotoxic T lymphocytes (CTL) were generated in mixed leukocyte cultures (MLC)
using spleen cells as responding cells and irradiated allogeneic spleen cells as stimulating …
using spleen cells as responding cells and irradiated allogeneic spleen cells as stimulating …
Regulation of the immune response to tumor antigens: I. Immunosuppressor cells in tumor-bearing hosts
S Fujimoto, MI Greene, AH Sehon - The Journal of Immunology, 1976 - journals.aai.org
A/Jax mice were rendered immune to the syngeneic and transplantable methylcholanthrene-
induced Sarcoma 1509a by the surgical removal of the tumor 7 days after implantation; …
induced Sarcoma 1509a by the surgical removal of the tumor 7 days after implantation; …
A comparison of the acute effects of radiation therapy, including or excluding the thymus, on the lymphocyte subpopulations of cancer patients.
JA Stratton, PE Byfield, JE Byfield… - The Journal of …, 1975 - Am Soc Clin Investig
Radiation therapy to either mediastinum or pelvis causes a rapid decrease in circulating
lymphocytes of both B and T types and in addition an impairment in the function of the …
lymphocytes of both B and T types and in addition an impairment in the function of the …
GENERATION OF CYTOTOXIC T LYMPHOCYTES IN VITRO: II. EFFECT OF REPEATED EXPOSURE TO ALLOANTIGENS ON THE CYTOTOXIC ACTIVITY OF LONG-TERM MIXED L …
HR MacDonald, HD Engers, JC Cerottini… - The Journal of …, 1974 - rupress.org
Mouse cytotoxic T lymphocytes (CTL) were generated in unidirectional mixed leukocyte
cultures (MLC) using normal C57BL/6 spleen cells as responding cells and irradiated DBA/2 …
cultures (MLC) using normal C57BL/6 spleen cells as responding cells and irradiated DBA/2 …
Cell‐mediated cell lysis in vitro: genetic control of killer cell production and target specificities in the mouse
M Nabholz, J Vives, HM Young, T Meo… - European journal of …, 1974 - Wiley Online Library
The requirements for killer cell production in the course of a mixed leukocyte reaction and
the specificity of target cell (PHA‐blasts) lysis in the mouse were investigated using inbred …
the specificity of target cell (PHA‐blasts) lysis in the mouse were investigated using inbred …
Properties of a subpopulation of T cells bearing histamine receptors.
M Plaut, LM Lichtenstein… - The Journal of Clinical …, 1975 - Am Soc Clin Investig
C57BL/6 mice immunized ip with alloantigen (P815 mastocytoma cells) develop cytolytically
active thymus-derived (T) splenic lymphocytes. The definition of specific histamine receptor …
active thymus-derived (T) splenic lymphocytes. The definition of specific histamine receptor …
Cell‐mediated reaction against tumors induced by oncornaviruses. I. Kinetics and specificity of the immune response in murine sarcoma virus (MSV)‐induced tumors …
JC Leclerc, E Gomard, JP Levy - International Journal of …, 1972 - Wiley Online Library
Anti‐tumour cell‐mediated immune reactions were studied by the chromium release test
(CRT) in mice bearing autochtonous Murine Sarcoma Virus (MSV)‐induced sarcomas or …
(CRT) in mice bearing autochtonous Murine Sarcoma Virus (MSV)‐induced sarcomas or …
Quantitative Studies on the Precursors of Cytotoxic Lymphocytes: I. Characterization of a Clonal Assay and Determination of the Size of Clones Derived from Single …
HS Teh, E Harley, RA Phillips… - The Journal of …, 1977 - journals.aai.org
A microculture system for estimating the frequency of cytotoxic lymphocyte precursors (CLP)
to alloantigens is described. Cytotoxic T lymphocytes (CL) were generated by culturing …
to alloantigens is described. Cytotoxic T lymphocytes (CL) were generated by culturing …