Astaxanthin as a king of ketocarotenoids: structure, synthesis, accumulation, bioavailability and antioxidant properties

A Nair, A Ahirwar, S Singh, R Lodhi, A Lodhi, A Rai… - Marine drugs, 2023 - mdpi.com
Astaxanthin (3, 3-dihydroxy-β, β-carotene-4, 4-dione) is a ketocarotenoid synthesized by
Haematococcus pluvialis/lacustris, Chromochloris zofingiensis, Chlorococcum …

Computational screening of natural compounds as putative quorum sensing inhibitors targeting drug resistance bacteria: Molecular docking and molecular dynamics …

K Chaieb, B Kouidhi, SB Hosawi… - Computers in Biology …, 2022 - Elsevier
Quorum sensing (QS) is a bacterial communication strategy controlling cells density, biofilm
formation, virulence, sporulation, and survival. Since QS is considered a virulence factor in …

Examining sialic acid derivatives as potential inhibitors of SARS-CoV-2 spike protein receptor binding domain

T Banerjee, A Gosai, N Yousefi… - Journal of …, 2024 - Taylor & Francis
Severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) has been the primary
reason behind the COVID-19 global pandemic which has affected millions of lives …

Evaluation of flavonoids as potential inhibitors of the SARS-CoV-2 main protease and spike RBD: Molecular docking, ADMET evaluation and molecular dynamics …

H Hadni, A Fitri, AT Benjelloun, M Benzakour… - Journal of the Indian …, 2022 - Elsevier
The 3CLpro main protease and the RDB spike (s) protein of SARS-CoV-2 are critical targets
in the treatment of coronavirus 19 disease (COVID-19), as they are responsible for the …

In silico molecular screening of bioactive natural compounds of rosemary essential oil and extracts for pharmacological potentials against rhinoviruses

D Singh, N Mittal, P Mittal, N Tiwari, SUD Khan… - Scientific Reports, 2024 - nature.com
Rhinoviruses (RVs) cause upper respiratory tract infections and pneumonia in children and
adults. These non-enveloped viruses contain viral coats of four capsid proteins: VP1, VP2 …

Identification of potential natural products derived from fungus growing termite, inhibiting Pseudomonas aeruginosa quorum sensing protein LasR using molecular …

M Shoaib, Y Ali, Y Shen, J Ni - Journal of Biomolecular Structure …, 2024 - Taylor & Francis
Pseudomonas aeruginosa, the most common opportunistic pathogen, is becoming antibiotic-
resistant worldwide. The fate of P. aeruginosa, a multidrug-resistant strain, can be …

Design and synthesis new indole-based aromatase/iNOS inhibitors with apoptotic antiproliferative activity

LH Al-Wahaibi, HA Abou-Zied… - Frontiers in …, 2024 - frontiersin.org
The present study details the design, synthesis, and bio-evaluation of indoles 3–16 as dual
inhibitors of aromatase and inducible nitric oxide synthase (iNOS) with antiproliferative …

Identification of fungus-growing termite-associated halogenated-PKS maduralactomycin a as a potential inhibitor of MurF protein of multidrug-resistant Acinetobacter …

M Shoaib, I Shehzadi, MU Asif, Y Shen… - Frontiers in Molecular …, 2023 - frontiersin.org
Multidrug-resistant Acinetobacter baumannii infections have become a major public health
concern globally. Inhibition of its essential MurF protein has been proposed as a potential …