[HTML][HTML] Reimagining the status quo: How close are we to rapid sputum-free tuberculosis diagnostics for all?

RR Nathavitharana, AL Garcia-Basteiro, M Ruhwald… - …, 2022 - thelancet.com
Rapid, accurate, sputum-free tests for tuberculosis (TB) triage and confirmation are urgently
needed to close the widening diagnostic gap. We summarise key technologies and review …

Rapid Diagnosis of Drug-Resistant Tuberculosis–Opportunities and Challenges

K Naidoo, R Perumal, SL Ngema, L Shunmugam… - Pathogens, 2023 - mdpi.com
Global tuberculosis (TB) eradication is undermined by increasing prevalence of emerging
resistance to available drugs, fuelling ongoing demand for more complex diagnostic and …

What is New in the Diagnosis of Childhood Tuberculosis?

C Rodrigues, T Singhal - Indian Journal of Pediatrics, 2024 - Springer
The fact that almost half of the 1 million cases of childhood tuberculosis (TB) globally remain
undiagnosed jeopardizes the TB elimination goal. Fortunately, there are new advances in …

[HTML][HTML] Updating the WHO target product profile for next-generation Mycobacterium tuberculosis drug susceptibility testing at peripheral centres

ELH MacLean, P Miotto… - PLOS global public …, 2023 - journals.plos.org
There were approximately 10 million tuberculosis (TB) cases in 2020, of which 500,000
were drug-resistant. Only one third of drug-resistant TB cases were diagnosed and enrolled …

Effective combination of isoniazid and core-shell magnetic nanoradiotherapy against gastrointestinal tumor cell types

H Chen, D Zhu, L Guo, G Li - International Journal of …, 2022 - Taylor & Francis
Introduction Radiotherapy is a conventional treatment for gastrointestinal tumors. However,
its therapeutic effect might not be satisfactory because of factors such as radio-resistance of …

What's New in the Molecular Diagnosis of Childhood Tuberculosis?

A Shaikh, C Rodrigues - The Pediatric Infectious Disease Journal, 2023 - journals.lww.com
Sample collection in children to detect tuberculosis (TB) is a vital consideration in achieving
a microbiologic diagnosis. 1 In children who have difficulty expectorating sputum …

[HTML][HTML] Feasibility, ease-of-use, and Operational Characteristics of World Health Organization–recommended moderate-complexity automated nucleic acid …

A David, M de Vos, L Scott, P da Silva, A Trollip… - The Journal of Molecular …, 2023 - Elsevier
Four moderate-complexity automated nucleic acid amplification tests for the diagnosis of
tuberculosis are reported as having laboratory analytical and clinical performance similar to …

[HTML][HTML] Tuberkulose im Erwachsenenalter

T Schaberg, F Brinkmann, C Feiterna-Sperling… - …, 2022 - thieme-connect.com
Die Tuberkulose ist in Deutschland eine seltene, überwiegend gut behandelbare
Erkrankung. Weltweit ist sie eine der häufigsten Infektionserkrankungen mit ca. 10 Millionen …

Exploring Diagnostic Methods for Drug-Resistant Tuberculosis: A Comprehensive Overview

A Sanchini, A Lanni, F Giannoni, A Mustazzolu - Tuberculosis, 2024 - Elsevier
Despite available global efforts and funding, Tuberculosis (TB) continues to affect a
considerable number of patients worldwide. Policy makers and stakeholders set clear goals …

[HTML][HTML] Determining cost and placement decisions for moderate complexity NAATs for tuberculosis drug susceptibility testing

A Malhotra, R Thompson, M De Vos, A David… - Plos one, 2023 - journals.plos.org
Background Access to drug resistant testing for tuberculosis (TB) remains a challenge in
high burden countries. Recently, the World Health Organization approved the use of several …