Animal models in eye research: focus on corneal pathologies

A Loiseau, G Raîche-Marcoux, C Maranda… - International Journal of …, 2023 - mdpi.com
The eye is a complex sensory organ that enables visual perception of the world. The
dysfunction of any of these tissues can impair vision. Conduction studies on laboratory …

The rabbit as an experimental and production animal: from genomics to proteomics

I Miller, C Rogel-Gaillard, D Spina… - Current Protein and …, 2014 - ingentaconnect.com
The rabbit (Oryctolagus cuniculus) is an important animal species widely used for
biomedical research purposes, meat production and as a pet animal. There are numerous …

[HTML][HTML] Use of rabbit eyes in pharmacokinetic studies of intraocular drugs

SJ Ahn, HK Hong, YM Na, SJ Park, J Ahn… - Journal of visualized …, 2016 - ncbi.nlm.nih.gov
The intraocular route of drug administration enables the delivery of high concentrations of
therapeutic drugs, while minimizing their systemic absorption. Several drugs are …

Comprehensive spectral libraries for various rabbit eye tissue proteomes

G Qin, P Zhang, M Sun, W Fu, C Cai - Scientific Data, 2022 - nature.com
Rabbits have been widely used for studying ocular physiology and pathology due to their
relatively large eye size and similar structures with human eyes. Various rabbit ocular …

Proteome alterations in the aqueous humor reflect structural and functional phenotypes in patients with advanced normal-tension glaucoma

SH Lee, JH Jung, TK Park, CE Moon, K Han, J Lee… - Scientific reports, 2022 - nature.com
Previous reports have shown possible association between altered protein levels in
aqueous humor (AH) and normal-tension glaucoma (NTG), but the underlying pathogenetic …

Proteomic analysis of the aqueous humor in patients with wet age‐related macular degeneration

J Yao, X Liu, Q Yang, M Zhuang, F Wang… - PROTEOMICS …, 2013 - Wiley Online Library
Purpose A number of studies have shown that the levels of some proteins in the aqueous
humor (AH) are altered and correlate with the mechanisms or prognosis of many eye …

Treatment of endotoxin-induced uveitis by topical application of cyclosporine a-loaded PolyGel™ in rabbit eyes

A Alshamsan, MA Kalam, MR Vakili… - International Journal of …, 2019 - Elsevier
The main objective of this study was to investigate the potential of poly (α-carboxylate-co-α-
benzylcarboxylate-ε-caprolactone)-block-poly (ethylene glycol)-block-poly (α-carboxylate-co …

[HTML][HTML] Proteomic analysis in pterygium; upregulated protein expression of ALDH3A1, PDIA3, and PRDX2

SW Kim, J Lee, B Lee, T Rhim - Molecular Vision, 2014 - ncbi.nlm.nih.gov
Purpose To identify differentially expressed proteins in the pterygium compared to healthy
conjunctiva using a proteomic analysis. Methods Pterygial and healthy conjunctival tissues …

Cancer cell resistance to aurora kinase inhibitors: identification of novel targets for cancer therapy

R Hrabakova, M Kollareddy, J Tyleckova… - Journal of proteome …, 2013 - ACS Publications
Drug resistance is the major obstacle to successful cancer therapy. Our study focuses on
resistance to Aurora kinase inhibitors tested as anti-cancer drugs in clinical trials. We have …

RETRACTED: Comparative study of the ciliary body and iris morphology in the anterior eye chamber of five different vertebrate classes

AA Seleem, AH Badr - Anatomia, Histologia, Embryologia, 2024 - Wiley Online Library
One crucial component of the optical system is the ciliary body (CB). This body secretes the
aqueous humour, which is essential to maintain the internal eye pressure as well as the …