Non-lethal outcomes of engaging regulated cell death pathways in cancer
Regulated cell death (RCD) is essential for successful systemic cancer therapy. Yet, the
engagement of RCD pathways does not inevitably result in cell death. Instead, RCD …
engagement of RCD pathways does not inevitably result in cell death. Instead, RCD …
The role of prostaglandins in different types of cancer
Á Jara-Gutiérrez, V Baladrón - Cells, 2021 - mdpi.com
The prostaglandins constitute a family of lipids of 20 carbon atoms that derive from
polyunsaturated fatty acids such as arachidonic acid. Traditionally, prostaglandins have …
polyunsaturated fatty acids such as arachidonic acid. Traditionally, prostaglandins have …
From conventional to precision therapy in canine mammary cancer: a comprehensive review
G Valdivia, Á Alonso-Diez, D Pérez-Alenza… - Frontiers in veterinary …, 2021 - frontiersin.org
Canine mammary tumors (CMTs) are the most common neoplasm in intact female dogs.
Canine mammary cancer (CMC) represents 50% of CMTs, and besides surgery, which is the …
Canine mammary cancer (CMC) represents 50% of CMTs, and besides surgery, which is the …
Embryonal erythropoiesis and aging exploit ferroptosis
H Zheng, L Jiang, T Tsuduki, M Conrad, S Toyokuni - Redox biology, 2021 - Elsevier
Ferroptosis is a form of regulated cell necrosis, as a consequence of Fe (II)-dependent lipid
peroxidation. Although ferroptosis has been linked to cancer cell death, neurodegeneration …
peroxidation. Although ferroptosis has been linked to cancer cell death, neurodegeneration …
Novel 1, 3-diaryl pyrazole derivatives bearing methylsulfonyl moiety: Design, synthesis, molecular docking and dynamics, with dual activities as anti-inflammatory and …
AMM Shaker, MI Shahin, AM AboulMagd… - Bioorganic …, 2022 - Elsevier
Three series of novel 1-aryl-3-(4-methylsulfonylphenyl) pyrazole derivatives were
synthesized, characterized by several spectroscopic techniques, and investigated as …
synthesized, characterized by several spectroscopic techniques, and investigated as …
Mechanisms of cancer cell death induction by triptolide
AH AbdulHussein, MM Al‐Taee, ZA Radih… - …, 2023 - Wiley Online Library
Drug resistance is a hot topic issue in cancer research and therapy. Although cancer therapy
including radiotherapy and anti‐cancer drugs can kill malignant cells within the tumor …
including radiotherapy and anti‐cancer drugs can kill malignant cells within the tumor …
New pyrimidine-5-carbonitriles as COX-2 inhibitors: design, synthesis, anticancer screening, molecular docking, and in silico ADME profile studies
Two series of cyanopyrimidine hybrids were synthesized bearing either benzo [d] imidazole,
benzo [d] oxazole, benzo [d] thiazole, and benzo [b] thiophene derivatives via methylene …
benzo [d] oxazole, benzo [d] thiazole, and benzo [b] thiophene derivatives via methylene …
Cinnamomum zeylanicum Extract and its Bioactive Component Cinnamaldehyde Show Anti-Tumor Effects via Inhibition of Multiple Cellular Pathways
S Aggarwal, K Bhadana, B Singh, M Rawat… - Frontiers in …, 2022 - frontiersin.org
Cinnamomum zeylanicum is a tropical plant with traditional medicinal significance that
possesses antimicrobial, antifungal, anti-parasitic, and anti-tumor properties. Here, we have …
possesses antimicrobial, antifungal, anti-parasitic, and anti-tumor properties. Here, we have …
Potential of the Compounds from Bixa orellana Purified Annatto Oil and Its Granules (Chronic®) against Dyslipidemia and Inflammatory Diseases: In Silico Studies …
MA Batista, AVT de Lima Teixeira dos Santos… - Molecules, 2022 - mdpi.com
Some significant compounds present in annatto are geranylgeraniol and tocotrienols. These
compounds have beneficial effects against hyperlipidemia and chronic diseases, where …
compounds have beneficial effects against hyperlipidemia and chronic diseases, where …
[HTML][HTML] Molecular mechanisms of resveratrol as chemo and radiosensitizer in cancer
S Cotino-Nájera, LA Herrera… - Frontiers in …, 2023 - frontiersin.org
One of the primary diseases that cause death worldwide is cancer. Cancer cells can be
intrinsically resistant or acquire resistance to therapies and drugs used for cancer treatment …
intrinsically resistant or acquire resistance to therapies and drugs used for cancer treatment …