From conventional to precision therapy in canine mammary cancer: a comprehensive review
G Valdivia, Á Alonso-Diez, D Pérez-Alenza… - Frontiers in veterinary …, 2021 - frontiersin.org
Canine mammary tumors (CMTs) are the most common neoplasm in intact female dogs.
Canine mammary cancer (CMC) represents 50% of CMTs, and besides surgery, which is the …
Canine mammary cancer (CMC) represents 50% of CMTs, and besides surgery, which is the …
Non-lethal outcomes of engaging regulated cell death pathways in cancer
Regulated cell death (RCD) is essential for successful systemic cancer therapy. Yet, the
engagement of RCD pathways does not inevitably result in cell death. Instead, RCD …
engagement of RCD pathways does not inevitably result in cell death. Instead, RCD …
The role of prostaglandins in different types of cancer
Á Jara-Gutiérrez, V Baladrón - Cells, 2021 - mdpi.com
The prostaglandins constitute a family of lipids of 20 carbon atoms that derive from
polyunsaturated fatty acids such as arachidonic acid. Traditionally, prostaglandins have …
polyunsaturated fatty acids such as arachidonic acid. Traditionally, prostaglandins have …
Embryonal erythropoiesis and aging exploit ferroptosis
H Zheng, L Jiang, T Tsuduki, M Conrad, S Toyokuni - Redox biology, 2021 - Elsevier
Ferroptosis is a form of regulated cell necrosis, as a consequence of Fe (II)-dependent lipid
peroxidation. Although ferroptosis has been linked to cancer cell death, neurodegeneration …
peroxidation. Although ferroptosis has been linked to cancer cell death, neurodegeneration …
Small-molecule compounds boost CAR-T cell therapy in hematological malignancies
X Cao, X Jin, X Zhang, P Utsav, Y Zhang, R Guo… - … Treatment Options in …, 2023 - Springer
Opinion statement Although chimeric antigen receptor T cell immunotherapy has been
successfully applied in patients with hematological malignancies, several obstacles still …
successfully applied in patients with hematological malignancies, several obstacles still …
Novel 1, 3-diaryl pyrazole derivatives bearing methylsulfonyl moiety: Design, synthesis, molecular docking and dynamics, with dual activities as anti-inflammatory and …
AMM Shaker, MI Shahin, AM AboulMagd… - Bioorganic …, 2022 - Elsevier
Three series of novel 1-aryl-3-(4-methylsulfonylphenyl) pyrazole derivatives were
synthesized, characterized by several spectroscopic techniques, and investigated as …
synthesized, characterized by several spectroscopic techniques, and investigated as …
Molecular mechanisms of resveratrol as chemo and radiosensitizer in cancer
S Cotino-Nájera, LA Herrera… - Frontiers in …, 2023 - frontiersin.org
One of the primary diseases that cause death worldwide is cancer. Cancer cells can be
intrinsically resistant or acquire resistance to therapies and drugs used for cancer treatment …
intrinsically resistant or acquire resistance to therapies and drugs used for cancer treatment …
COX 2-inhibitors; a thorough and updated survey into combinational therapies in cancers
Cyclooxygenase (COX) enzymes are pivotal in inflammation and cancer development. COX-
2, in particular, has been implicated in tumor growth, angiogenesis, and immune evasion …
2, in particular, has been implicated in tumor growth, angiogenesis, and immune evasion …
Simultaneous encapsulation of dasatinib and celecoxib into caseinate micelles towards improved in vivo anti-breast cancer efficacy with reduced drug toxicity
Breast cancer is the most global dominant cancer among females. Although there are
continuously growing strategies to develop new therapies, the outcomes are usually …
continuously growing strategies to develop new therapies, the outcomes are usually …
Synthesis of new imidazole-triazole-glycoside hybrids as anti-breast cancer candidates
WI El-Sofany, WA El-sayed, AA Abd-Rabou… - Journal of Molecular …, 2022 - Elsevier
One of the leading causes of death worldwide among women is breast cancer. Thus,
discovering new multi-target anti-breast cancer drugs is mandatory to stimulate nitric oxide …
discovering new multi-target anti-breast cancer drugs is mandatory to stimulate nitric oxide …