Canine mammary tumors (CMTs) are the most common neoplasm in intact female dogs.
Canine mammary cancer (CMC) represents 50% of CMTs, and besides surgery, which is the …

Regulated cell death (RCD) is essential for successful systemic cancer therapy. Yet, the
engagement of RCD pathways does not inevitably result in cell death. Instead, RCD …

The prostaglandins constitute a family of lipids of 20 carbon atoms that derive from
polyunsaturated fatty acids such as arachidonic acid. Traditionally, prostaglandins have …

Ferroptosis is a form of regulated cell necrosis, as a consequence of Fe (II)-dependent lipid
peroxidation. Although ferroptosis has been linked to cancer cell death, neurodegeneration …

Opinion statement Although chimeric antigen receptor T cell immunotherapy has been
successfully applied in patients with hematological malignancies, several obstacles still …

Three series of novel 1-aryl-3-(4-methylsulfonylphenyl) pyrazole derivatives were
synthesized, characterized by several spectroscopic techniques, and investigated as …

One of the primary diseases that cause death worldwide is cancer. Cancer cells can be
intrinsically resistant or acquire resistance to therapies and drugs used for cancer treatment …

Cyclooxygenase (COX) enzymes are pivotal in inflammation and cancer development. COX-
2, in particular, has been implicated in tumor growth, angiogenesis, and immune evasion …

Breast cancer is the most global dominant cancer among females. Although there are
continuously growing strategies to develop new therapies, the outcomes are usually …

One of the leading causes of death worldwide among women is breast cancer. Thus,
discovering new multi-target anti-breast cancer drugs is mandatory to stimulate nitric oxide …