Diagnosing antiphospholipid syndrome:'extra-criteria'manifestations and technical advances

S Sciascia, MC Amigo, D Roccatello… - Nature Reviews …, 2017 - nature.com
First described in the early 1980s, antiphospholipid syndrome (APS) is a unique form of
acquired autoimmune thrombophilia in which patients present with clinical features of …

[HTML][HTML] Laboratory diagnosis of antiphospholipid syndrome: insights and hindrances

A Vandevelde, KMJ Devreese - Journal of Clinical Medicine, 2022 - mdpi.com
Diagnosis of antiphospholipid syndrome (APS) requires the presence of a clinical criterion
(thrombosis and/or pregnancy morbidity), combined with persistently circulating …

Current treatment of antiphospholipid syndrome: lights and shadows

G Espinosa, R Cervera - Nature Reviews Rheumatology, 2015 - nature.com
For patients with antiphospholipid syndrome (APS), the consensus is to treat those who
develop thrombosis with long-term oral anticoagulation therapy and to prevent obstetric …

Diagnosis and management of the antiphospholipid syndrome

S Chaturvedi, KR McCrae - Blood reviews, 2017 - Elsevier
Antiphospholipid syndrome (APS) is characterized by thrombosis and/or pregnancy
complications in the presence of persistent antiphospholipid antibodies (APLA). Laboratory …

[HTML][HTML] The weight of IgA anti-β2glycoprotein I in the antiphospholipid syndrome pathogenesis: closing the gap of seronegative antiphospholipid syndrome

O Cabrera-Marante, E Rodríguez de Frías… - International Journal of …, 2020 - mdpi.com
The specific value of IgA Anti-β2glycoprotein I antibodies (aB2GP1) in the diagnosis and
management of antiphospholipid syndrome (APS) is still controversial and a matter of active …

[HTML][HTML] Added value of non-criteria antiphospholipid antibodies for antiphospholipid syndrome: lessons learned from year-long routine measurements

P Žigon, A Podovšovnik, A Ambrožič, M Tomšič… - Clinical …, 2019 - Springer
The international classification criteria for definite antiphospholipid syndrome (APS) include
three laboratory measurements: lupus anticoagulant (LA), IgG and IgM isotypes of anti …

[HTML][HTML] Pediatric antiphospholipid syndrome: from pathogenesis to clinical management

S Rosina, CB Chighizola, A Ravelli… - Current rheumatology …, 2021 - Springer
Abstract Purpose of Review Elucidating the pathogenic mechanisms mediated by
antiphospholipid antibodies (aPL) might exert important clinical implications in pediatric …

Is there an additional value in detecting anticardiolipin and anti-β2 glycoprotein I IgA antibodies in the antiphospholipid syndrome?

W Chayoua, D Yin, H Kelchtermans… - Thrombosis and …, 2020 - thieme-connect.com
Background Anticardiolipin (aCL) and anti-β2 glycoprotein I (aβ2GPI) immunoglobulin A
(IgA) antiphospholipid antibodies (aPL) have shown to associate with thrombosis and …

Anti‐phospholipid antibodies and reproductive failures

A Beltagy, L Trespidi, M Gerosa… - American Journal of …, 2021 - Wiley Online Library
Anti‐phospholipid syndrome (APS) recapitulates the link between autoimmunity and
pregnancy failure: Acquired anti‐phospholipid antibodies (aPL) play a pathogenic role in …

Update on the pathogenesis and treatment of the antiphospholipid syndrome

CB Chighizola, E Raschi, MO Borghi… - Current opinion in …, 2015 - journals.lww.com
Update on the pathogenesis and treatment of the antiphosphol... : Current Opinion in
Rheumatology Update on the pathogenesis and treatment of the antiphospholipid syndrome …