For elderly patients with locally advanced esophageal cancer, therapeutic approaches and
outcomes in a modern cohort are not well characterized. Patients≥ 70 years old with clinical …

Little evidence is available about survival rates in patients with recurrent disease after
potentially curative surgery for esophageal or junctional cancer. Only in limited occasions …

Aurora A kinase is a cell cycle regulator that is dysregulated in several different
malignancies. Nevertheless, its regulatory mechanisms are still not fully understood. Here …

Importance Palliative radiotherapy (RT) is generally recommended for older patients with
esophageal squamous cell carcinoma (ESCC) with poor prognosis. A new combination …

To investigate the prognostic value of the Geriatric Nutritional Risk Index (GNRI) in
esophageal squamous cell carcinoma (ESCC) patients treated with radiotherapy (RT) or …

Purpose: The reported data of elderly ESCC are rather limited and there is a lack of
information to guide treatment decisions for elderly patients with esophageal cancer. This …

Purpose: To develop and validate a prediction model for nonoperative EGFR-positive locally
advanced elderly esophageal cancer (LAEEC). Methods: Eighty EGFR-positive LAEEC …

Esophageal cancer (EC) is a common digestive tract malignant tumor and the clinical
outcome of patients with EC after surgery remains unsatisfactory. Hence, it is necessary to …

Background We describe a novel scoring system, namely the inflammatory response
biomarker (IRB) score. The aim of this study is to evaluate the clinical value of IRB score in …

Background To evaluate the feasibility and efficiency of definitive concurrent
chemoradiotherapy (dCRT) with S-1 and cisplatin for elderly esophageal squamous cell …