There is increasing evidence for an association between periodontitis/tooth loss and oral,
gastrointestinal, and pancreatic cancers. Periodontal disease, which is characterized by …

Epigenetic modifications occur in response to environmental changes and play a
fundamental role in gene expression following environmental stimuli. Major epigenetic …

An association between oral disease/periodontitis and rheumatoid arthritis (RA) has been
considered since the early 1820s. The early treatment was tooth eradication …

Periodontitis is a common chronic inflammatory disease that is initiated by a complex
microbial biofilm that poses significant health and financial burdens globally …

Periodontitis is a chronic oral inflammatory disease produced by bacteria. Gingival retraction
and bone and connective tissues resorption are the hallmarks of this disease. Chronic …

Periodontitis is a multifactorial disease that causes tooth loss. The complex pathogenesis of
periodontitis implies the involvement of a susceptible host and a bacterial challenge. Many …

There is a significant prevalence of subjects with periodontitis presenting with other
inflammatory conditions such as coronary heart disease, insulin resistance and arthritis. This …

Defects, as determined by Genome-Wide Association Studies (GWAS), in the complement
cascade of innate immunity have been suggested to play a key role in Alzheimer's disease …

Numerous studies have demonstrated significant associations between periodontal disease
and many other diseases in living populations, and some studies have shown that …

Genetic information such as DNA sequences has been limited to fully explain mechanisms
of gene regulation and disease process. Epigenetic mechanisms, which include DNA …