Simple Summary Melanoma is a major public health issue that claims the lives of thousands
of people every year. Furthermore, the outlook for the coming years is not encouraging with …

Melanoma is one of the most aggressive malignancies of the skin. The genetic composition
of melanoma is complex and varies among different subtypes. With the aid of recent …

Melanoma, a malignant form of skin cancer, has been swiftly increasing in recent years.
Although there have been significant advancements in clinical treatment underlying a well …

Cutaneous melanoma (CM) is a multifactorial disease whose treatment still presents
challenges: the rapid progression to advanced CM, which leads to frequent recurrences …

Malignant melanoma has shown an increasing incidence during the last two decades,
exhibiting a large spectrum of locations and clinicopathological characteristics. Although …

Melanoma, originating through malignant transformation of melanin-producing melanocytes,
is a formidable malignancy, characterized by local invasiveness, recurrence, early …

Simple Summary Skin cancer is a common, preventable condition of global importance.
Different types of skin cancer, like melanoma, basal cell carcinoma, and squamous cell …

We introduce drexml, a command line tool and Python package for rational data-driven drug
repurposing. The package employs machine learning and mechanistic signal transduction …

Simple Summary Melanoma is the third most common type of skin cancer. Melanoma is a
heterogeneous tumor, composed of genetically divergent subpopulations. These …

Abstract Protection of Telomeres Protein 1 (POT1) protein is an essential subunit of the
shelterin telomere binding complex, regulating telomere length. Some POT1 gene …