The basal forebrain cholinergic neurons (BFCN) provide the primary source of cholinergic
innervation of the human cerebral cortex. They are involved in the cognitive processes of …

Some 50 years have elapsed since Elliot et al. and MacIntosh & Oborin first reported a
release of acetylcholine (ACh) from canine and feline cerebral cortices, respectively. In this …

The reasons for the selective vulnerability of distinct neuronal populations in
neurodegenerative disorders are unknown. The cholinergic neurons of the basal forebrain …

Cholinergic neurons of the basal forebrain (BFCN) are selectively vulnerable in
neurodegenerative disorders of the elderly, particularly in Alzheimer's disease (AD). We …

A relatively early and substantial loss of basal forebrain cholinergic neurons is a constant
feature of Alzheimer's disease (AD). However, the mechanisms that contribute to the …

A mouse monoclonal antibody (clone 62‐2E8) raised against a human recombinant high‐
affinity choline transporter (CHT)‐glutathione‐S‐transferase fusion protein was used to …

Aims Galanin is a highly inducible neuroprotective neuropeptide and in Alzheimer's disease
(AD), a network of galaninergic fibres has been reported to hypertrophy and hyperinnervate …

Cholinergic innervation of the frontal cortex is important in higher cognitive functions and
may have been altered in humans relative to other species to support human‐specific …

The non-selective muscarinic receptor antagonist scopolamine (SCP) induces memory
deficits in both animals and humans. However, few studies have assessed the effects of …

Long projection axons from the Ch4 cell group of the nucleus basalis of Meynert (nbM)
provide cholinergic innervation to the neurons of the cerebral cortex. This cortical cholinergic …