A metabolic bone disorder called osteoporosis is characterized by decreased bone mass
and compromised microarchitecture. This condition can deteriorate bones and raise the risk …

Purpose Bone diseases account for an enormous cost burden on health systems. Bone
disorders are considered as age-dependent diseases. The aging of world population has …

Steroid‐induced osteoporosis (SIOP) is a form of secondary osteoporosis, but its specific
mechanism remains unclear. Glucocorticoid (GC‐)‐induced death of osteoblasts and bone …

Rotator cuff tear is the main form of shoulder joint injury, which seriously affects shoulder
joint function. This study aimed to clarify the function and mechanism of exosomes …

Glucocorticoid-induced osteonecrosis of the femoral head (GIONFH) is the main
complication secondary to long-term or excessive glucocorticoid use. Promoting …

Melatonin is an important endogenous hormone that modulates homeostasis in the
microenvironment. Recent studies have indicated that serum melatonin levels are closely …

There is a vast pre-clinical literature suggesting that certain nutraceuticals have the potential
to aid the preservation of bone mass in the context of estrogen withdrawal, glucocorticoid …

Abstract Glucocorticoid (GC)‐induced osteoporosis (GIO) is a concurrent disease commonly
appeared in chronic inflammatory and autoimmune disease patients. Stereoselective …

Melatonin is a bioamine produced primarily in the pineal gland, although peripheral sites,
including the gut, may also be its minor source. Melatonin regulates various functions …

Increasing bone resorption followed by decreasing bone mineralization are hallmarks of
bone degeneration, which mostly occurs in the elderly population and post-menopausal …