Natural product-based nanoformulations for cancer therapy: Opportunities and challenges

D Kashyap, HS Tuli, MB Yerer, A Sharma, K Sak… - Seminars in cancer …, 2021 - Elsevier
Application of natural product-based nanoformulations for the treatment of different human
diseases, such as cancer, is an emerging field. The conventional cancer therapeutic …

Gut microbiota, short-chain fatty acids, and herbal medicines

W Feng, H Ao, C Peng - Frontiers in pharmacology, 2018 - frontiersin.org
As an important source for traditional medical systems such as Ayurvedic medicine and
traditional Chinese medicine, herbal medicines have received widespread attentions from …

Generative molecular design in low data regimes

M Moret, L Friedrich, F Grisoni, D Merk… - Nature Machine …, 2020 - nature.com
Generative machine learning models sample molecules from chemical space without the
need for explicit design rules. To enable the generative design of innovative molecular …

[PDF][PDF] Coumarins from Red Delicious apple seeds: Extraction, phytochemical analysis, and evaluation as antimicrobial agents

ET Mohammed, YF Mustafa - Systematic Reviews in Pharmacy, 2020 - researchgate.net
The evolution of resistance to many valid antimicrobial agents and the demand for exploring
novel agents to deal with this emerge are wellhighlighted. In this report, the seeds of Red …

Plant secondary metabolites: an introduction of their chemistry and biological significance with physicochemical aspect

A Sharma, S Sharma, A Kumar, V Kumar… - … -chemical properties and …, 2022 - Springer
Nature is the immense source of chemical compounds or substances usually acknowledged
as natural products. Plants are the considerable source of an inestimable diversity of natural …

[PDF][PDF] Synthesis and biological activities of 3, 5-disubstituted-4-hydroxycinnamic acids linked to a functionalized coumarin

MK Oglah, MK Bashir, YF Mustafa, ET Mohammed… - Syst Rev …, 2020 - academia.edu
As part of our interest in the coumarin chemical nucleus, a series of 3, 5-disubstituted-4-
hydroxycinnamic acids to which 6-hydroxy-7-methoxy-4-methyl-3-isopropylcoumarin is …

Deep learning approaches for natural product discovery from plant endophytic microbiomes

SA Aghdam, AMV Brown - Environmental microbiome, 2021 - Springer
Plant microbiomes are not only diverse, but also appear to host a vast pool of secondary
metabolites holding great promise for bioactive natural products and drug discovery. Yet …

The health benefits of three Hedgenettle herbal teas (Stachys byzantina, Stachys inflata, and Stachys lavandulifolia)-profiling phenolic and antioxidant activities

MB Bahadori, G Zengin, L Dinparast… - European Journal of …, 2020 - Elsevier
Introduction Plants belonging to the genus Stachys have been used in traditional medicine
due to their various properties. The potential health benefits of three widely consumed …

Shaping the gut microbiota by bioactive phytochemicals: An emerging approach for the prevention and treatment of human diseases

S Sudheer, P Gangwar, Z Usmani, M Sharma… - Biochimie, 2022 - Elsevier
The human digestive tract is the cottage to trillions of live microorganisms, which regulate
health and illness. A healthy Gut Microbiota (GM) is necessary for preventing microbial …

[HTML][HTML] Unraveling the role of medicinal plants and Gut microbiota in colon cancer: Towards microbiota-based strategies for prevention and treatment

A Vignesh, TC Amal, S Selvakumar, K Vasanth - Health Sciences Review, 2023 - Elsevier
Colon cancer remains one of the leading causes of morbidity and mortality worldwide. Given
its widespread prevalence, the identification of new anticancer drugs is crucial. Medicinal …