An update on the genetics of hyperuricaemia and gout
A central aspect of the pathogenesis of gout is elevated urate concentrations, which lead to
the formation of monosodium urate crystals. The clinical features of gout result from an …
the formation of monosodium urate crystals. The clinical features of gout result from an …
The haplotype of SLC2A9_rs3733591, PKD2_rs2725220 and ABCG2_rs2231142 increases the hyperuricaemia risk and alcohol, chicken and processed meat …
HJ Yang, M Liu, MJ Kim, S Park - International Journal of Food …, 2021 - Taylor & Francis
We determined that a genetic haplotype increased the risk of hyperuricaemia and it
interacted with lifestyle factors, including nutrients in 28,445 middle-aged Koreans. ABCG2 …
interacted with lifestyle factors, including nutrients in 28,445 middle-aged Koreans. ABCG2 …
Epistatic interaction between PKD2 and ABCG2 influences the pathogenesis of hyperuricemia and gout
Background Genetic background affects serum urate concentration and gout risk, especially
regarding these variants in the urate-transporter gene ABCG2. However, the role of epistasis …
regarding these variants in the urate-transporter gene ABCG2. However, the role of epistasis …
Association of multiple SNPs at slc2a9 exon 8 in gout disease in Iraqi population: A molecular study
RS Ramdhan, NA Hade, RN Algafari - Meta Gene, 2021 - Elsevier
This work was planned to reveal changes in DNA sequence coding for GLUT9 by SLC2A9
gene at exon 8 that may be play a role in gout disease. For this reason 250 male and 150 …
gene at exon 8 that may be play a role in gout disease. For this reason 250 male and 150 …
An investigation into inflammasome-gene expression profile and genome-wide genotype data in gout
G Sandoval-Plata - 2022 - eprints.nottingham.ac.uk
Background: Gout is the most common form of inflammatory arthritis, with a prevalence of
2.49% in the United Kingdom. It is characterised by episodes of acute inflammation (flares) …
2.49% in the United Kingdom. It is characterised by episodes of acute inflammation (flares) …
Selection and Metabolic Disease in the Pacific
M Cadzow - 2018 - ourarchive.otago.ac.nz
An example of a" signature of selection" in a population is a region of the genome that
exhibits a reduction in genetic variability with a particular linkage disequilibrium pattern. This …
exhibits a reduction in genetic variability with a particular linkage disequilibrium pattern. This …
PKD2 influence uric acid levels and gout risk by interacting with ABCG2
Background Uric acid is the final product of purine metabolism and elevated serum urate
levels can cause gout. Conflicting results were reported for the effect of PKD2 on serum …
levels can cause gout. Conflicting results were reported for the effect of PKD2 on serum …
[PDF][PDF] ABCG2 and PKD2 polymorphisms correlate with gout-related metabolic indices in Chinese Han and Tibetan populations
Y Zhang, L Ma, Y Zhao, L Liu, Y Zhang, Z Zhang… - Int J Clin Exp …, 2017 - e-century.us
Gout is a complex inflammation disease resulting from an increase in serum uric acid (SUA),
which is one of the most common forms of inflammatory arthritis worldwide. Identification of …
which is one of the most common forms of inflammatory arthritis worldwide. Identification of …