[HTML][HTML] Natural compounds and glutathione: Beyond mere antioxidants

C Di Giacomo, GA Malfa, B Tomasello, S Bianchi… - Antioxidants, 2023 - mdpi.com
The tripeptide glutathione plays important roles in many cell processes, including
differentiation, proliferation, and apoptosis; in fact, disorders in glutathione homeostasis are …

[HTML][HTML] Effects of DNA, RNA, and Protein Methylation on the Regulation of Ferroptosis

X Wang, X Kong, X Feng, DS Jiang - International Journal of …, 2023 - ncbi.nlm.nih.gov
Ferroptosis is a form of programmed cell death characterized by elevated intracellular
ferrous ion levels and increased lipid peroxidation. Since its discovery and characterization …

Discovering a new drug against acute kidney injury by using a tailored photoacoustic imaging probe

W Zhang, C Chan, K Zhang, H Qin, BY Yu… - Advanced …, 2024 - Wiley Online Library
Acute kidney injury (AKI) has become an increasing concern for patients due to the
widespread clinical use of nephrotoxic drugs. Currently, the early diagnosis of AKI is still …

[HTML][HTML] Unleashing the power of porphyrin photosensitizers: illuminating breakthroughs in photodynamic therapy

A Alibasha, S Khan, T Chatterjee, M Ghosh - Journal of Photochemistry and …, 2023 - Elsevier
This comprehensive review provides the current trends and recent developments of
porphyrin-based photosensitizers. We discuss their evolution from first-generation to third …

Contribution of yeast and its biomass for the preparation of industrially essential materials: A boon to circular economy

AK Wani, F Rahayu, I Yustina, GSA Fatah… - Bioresource Technology …, 2023 - Elsevier
Yeast biomass, a valuable byproduct of various industrial processes, can help in minimizing
the environmental impact of industries by reducing the use of non-renewable resources and …

Revitalizing Ancient Mitochondria with Nano‐Strategies: Mitochondria‐Remedying Nanodrugs Concentrate on Disease Control

X Long, M Liu, Y Nan, Q Chen, Z Xiao… - Advanced …, 2024 - Wiley Online Library
Mitochondria, widely known as the energy factories of eukaryotic cells, have a myriad of vital
functions across diverse cellular processes. Dysfunctions within mitochondria serve as …

[HTML][HTML] Novel insights into the role of mitochondria in diabetic cardiomyopathy: molecular mechanisms and potential treatments

F Zhi, Q Zhang, L Liu, X Chang, H Xu - Cell Stress and Chaperones, 2023 - Elsevier
Diabetic cardiomyopathy describes decreased myocardial function in diabetic patients in the
absence of other heart diseases such as myocardial ischemia and hypertension. Recent …

GSK-3α aggravates inflammation, metabolic derangement, and cardiac injury post-ischemia/reperfusion

F Ahmad, H Marzook, A Gupta, A Aref, K Patil… - Journal of Molecular …, 2023 - Springer
Reperfusion after acute myocardial infarction further exaggerates cardiac injury and adverse
remodeling. Irrespective of cardiac cell types, loss of specifically the α isoform of the protein …

[HTML][HTML] Mitochondrial glutathione in cellular redox homeostasis and disease manifestation

TH Chen, HC Wang, CJ Chang, SY Lee - International Journal of …, 2024 - mdpi.com
Mitochondria are critical for providing energy to maintain cell viability. Oxidative
phosphorylation involves the transfer of electrons from energy substrates to oxygen to …

[HTML][HTML] Integration of transcriptomics, metabolomics, and lipidomics reveals the mechanisms of doxorubicin-induced inflammatory responses and myocardial …

X Tan, R Zhang, M Lan, C Wen, H Wang, J Guo… - Biomedicine & …, 2023 - Elsevier
Doxorubicin (DOX) is an anthracycline antineoplastic agent that has limited clinical utility
due to its dose-dependent cardiotoxicity. Although the exact mechanism remains unknown …