Recent strategies to develop innovative photosensitizers for enhanced photodynamic therapy
TC Pham, VN Nguyen, Y Choi, S Lee, J Yoon - Chemical reviews, 2021 - ACS Publications
This review presents a robust strategy to design photosensitizers (PSs) for various species.
Photodynamic therapy (PDT) is a photochemical-based treatment approach that involves the …
Photodynamic therapy (PDT) is a photochemical-based treatment approach that involves the …
Clinical development of metal complexes as photosensitizers for photodynamic therapy of cancer
J Karges - Angewandte chemie international edition, 2022 - Wiley Online Library
Cancer has emerged over the last decades as one of the deadliest diseases in the world.
Among the most commonly used techniques (ie surgery, immunotherapy, radiotherapy or …
Among the most commonly used techniques (ie surgery, immunotherapy, radiotherapy or …
Luminescent and photofunctional transition metal complexes: From molecular design to diagnostic and therapeutic applications
There has been emerging interest in the exploitation of the photophysical and
photochemical properties of transition metal complexes for diagnostic and therapeutic …
photochemical properties of transition metal complexes for diagnostic and therapeutic …
Near-infrared metal agents assisting precision medicine: from strategic design to bioimaging and therapeutic applications
C Li, Y Pang, Y Xu, M Lu, L Tu, Q Li… - Chemical Society …, 2023 - pubs.rsc.org
Metal agents have made incredible strides in preclinical research and clinical applications in
recent years, but their short emission/absorption wavelengths continue to be a barrier to …
recent years, but their short emission/absorption wavelengths continue to be a barrier to …
Latest developments in metal complexes as anticancer agents
R Paprocka, M Wiese-Szadkowska… - Coordination Chemistry …, 2022 - Elsevier
Every year novel biologically active compounds are designed as antitumor agents. This
review covers and highlights some of the most important findings described during 2018 …
review covers and highlights some of the most important findings described during 2018 …
Ferroptosis photoinduced by new cyclometalated iridium (III) complexes and its synergism with apoptosis in tumor cell inhibition
Limited therapeutic efficacy to hypoxic and refractory solid tumors has hindered the practical
application of photodynamic therapy (PDT). Two new benzothiophenylisoquinoline (btiq) …
application of photodynamic therapy (PDT). Two new benzothiophenylisoquinoline (btiq) …
A Metal‐Free Mesoporous Carbon Dots/Silica Hybrid Type I Photosensitizer with Enzyme‐Activity for Synergistic Treatment of Hypoxic Tumor
B Tian, S Liu, C Yu, S Liu, S Dong… - Advanced Functional …, 2023 - Wiley Online Library
As a less O2‐dependent photodynamic therapy (PDT), type I PDT is an effective approach to
overcome the hypoxia‐induced low efficiency against solid tumors. However, the commonly …
overcome the hypoxia‐induced low efficiency against solid tumors. However, the commonly …
Highly Efficient Far‐Red/NIR‐Absorbing Neutral Ir (III) Complex Micelles for Potent Photodynamic/Photothermal Therapy
A critical issue in photodynamic therapy (PDT) is inadequate reactive oxygen species (ROS)
generation in tumors, causing inevitable survival of tumor cells that usually results in tumor …
generation in tumors, causing inevitable survival of tumor cells that usually results in tumor …
Intraligand excited states turn a ruthenium oligothiophene complex into a light-triggered Ubertoxin with anticancer effects in extreme hypoxia
Ru (II) complexes that undergo photosubstitution reactions from triplet metal-centered (3MC)
excited states are of interest in photochemotherapy (PCT) due to their potential to produce …
excited states are of interest in photochemotherapy (PCT) due to their potential to produce …
A near-infrared light-activatable Ru (ii)-coumarin photosensitizer active under hypoxic conditions
E Ortega-Forte, A Rovira, M López-Corrales… - Chemical …, 2023 - pubs.rsc.org
Photodynamic therapy (PDT) represents a promising approach for cancer treatment.
However, the oxygen dependency of PDT to generate reactive oxygen species (ROS) …
However, the oxygen dependency of PDT to generate reactive oxygen species (ROS) …