Deciphering the Ligand's geometric effect on the photophysical properties of osmium complex and its application in triplet-triplet annihilation upconversion

Z Yuan, J He, Z Mahmood, L Xing, S Ji, Y Huo… - Dyes and …, 2022 - Elsevier
Osmium complex, which featured with direct S 0→ T 1 absorption, are of particular interest in
several photochemical applications including triplet-triplet annihilation (TTA) upconversion …

Enabling in vivo optical imaging of an osmium photosensitizer by micellar formulation

D Shah, M Eroy, J Fakhry, A Moffat, K Fritz, HD Cole… - Pharmaceutics, 2022 - mdpi.com
Osmium (Os)-based photosensitizers (PSs) exhibit unique broad, red-shifted absorption,
favoring PDT activity at greater tissue depths. We recently reported on a potent Os (II) PS …

Photophysical Properties and DNA Binding of Two Intercalating Osmium Polypyridyl Complexes Showing Light-Switch Effects

M Stitch, RZ Boota, AS Chalkley, TD Keene… - Inorganic …, 2022 - ACS Publications
The synthesis and photophysical characterization of two osmium (II) polypyridyl
complexes,[Os (TAP) 2dppz] 2+(1) and [Os (TAP) 2dppp2] 2+(2) containing dppz (dipyrido …

Dinuclear Tridentate Ru (II) Complex with Strong Near-Infrared Light-Triggered Anticancer Activity

L Wei, R Kushwaha, T Sadhukhan, H Wu… - Journal of Medicinal …, 2024 - ACS Publications
The design of the dinuclear Ru (II) complex (Ru2) with strong near-infrared (NIR) absorption
properties has been reported for efficient anticancer phototherapy. Under 700 nm LED light …

Photoinduced Carbene for Effective Photodynamic Therapy Against Hypoxic Cancer Cells

Z Sun, Y Chen, S Yao, H Yuan, D Song, Z Guo… - CCS …, 2023 - chinesechemsoc.org
Photodynamic therapy (PDT) has attracted much attention because of its advantages over
chemotherapy, such as broad spectrum, high selectivity, and low drug resistance. However …

Cyclometalated Iridium(III) Complexes as Mitochondria‐targeting Photosensitizers against Cisplatin‐resistant Cells

K Xiong, Y Zhou, X Lin, J Kou, M Lin… - Photochemistry and …, 2022 - Wiley Online Library
Four iridium (III) complexes Ir1‐Ir4 were synthesized and characterized. Possessing high
singlet oxygen production ability and specific mitochondria‐localization, Ir1 was developed …

Establishing a Robust and Reliable Response from a Potent Osmium‐Based Photosensitizer Via Lipid Nanoformulation

HD Cole, M Eroy, JA Roque III, G Shi… - Photochemistry and …, 2023 - Wiley Online Library
Abstract Osmium (Os) based photosensitizers (PSs) are a unique class of nontetrapyrrolic
metal‐containing PSs that absorb red light. We recently reported a highly potent Os (II) PS …

Ru (II) Oligothienyl Complexes with Fluorinated Ligands: Photophysical, Electrochemical, and Photobiological Properties

HD Cole, A Vali, JA Roque III, G Shi… - Inorganic …, 2024 - ACS Publications
A series of Ru (II) complexes incorporating two 4, 4′-bis (trifluoromethyl)-2, 2′-bipyridine
(4, 4′-btfmb) coligands and thienyl-appended imidazo [4, 5-f][1, 10] phenanthroline (IP-n T) …

Chiral resolution and absolute configuration determination of new metal-based photodynamic therapy antitumor agents

DW Armstrong, J Yu, HD Cole, SA McFarland… - … of pharmaceutical and …, 2021 - Elsevier
The advent of cisplatin as a cancer drug in the late 1960s generated considerable interest in
the use of transition metal complexes as cancer therapy agents. Despite enhanced research …

Klinische Entwicklung von Metallkomplexen als Photosensibilisatoren für die photodynamische Therapie von Krebs

J Karges - Angewandte Chemie, 2022 - Wiley Online Library
Krebs hat sich in den letzten Jahrzehnten zu einer der häufigsten krankheitsbedingten
Todesursachen der Welt entwickelt. Neben den am häufigsten angewendeten Techniken …