[HTML][HTML] Proteomic quantification of native and ECM-enriched mouse ovaries reveals an age-dependent fibro-inflammatory signature

SS Dipali, CD King, JP Rose, JE Burdette… - Aging (Albany …, 2023 - ncbi.nlm.nih.gov
The ovarian microenvironment becomes fibrotic and stiff with age, in part due to increased
collagen and decreased hyaluronan. However, the extracellular matrix (ECM) is a complex …

[HTML][HTML] PPARβ/δ Ligands Regulate Oxidative Status and Inflammatory Response in Inflamed Corpus Luteum—An In Vitro Study

K Mierzejewski, A Kurzyńska, Z Gerwel… - International Journal of …, 2023 - mdpi.com
Inflammation in the female reproductive system causes serious health problems including
infertility. The aim of this study was to determine the in vitro effects of peroxisome proliferator …

In vitro effects of PPAR gamma ligands on gene expression in corpus luteum explants in non-pregnant pigs-Transcriptome analysis

K Mierzejewski, Z Gerwel, A Kurzyńska, M Golubska… - Theriogenology, 2023 - Elsevier
The corpus luteum (CL) is a temporary endocrine structure in the female ovaries that
develops cyclically in mature females during luteinization. This study aimed to determine the …

PPAR beta/delta regulates the immune response mechanisms in the porcine endometrium during LPS-induced inflammation–an in vitro study

M Golubska, Ł Paukszto, A Kurzyńska, K Mierzejewski… - Theriogenology, 2024 - Elsevier
Inflammation in the reproductive tract has become a serious threat to animal fertility.
Recently, the role of peroxisome proliferator-activated receptor gamma (PPARγ) in the …