The epidemiology of epilepsy in Europe–a systematic review

L Forsgren, E Beghi, A Oun… - European Journal of …, 2005 - Wiley Online Library
Population‐based epidemiological studies on epilepsy are available mainly from the UK
and the Nordic, Baltic and western Mediterranean countries. No studies were identified from …

Drug resistance in epilepsy: putative neurobiologic and clinical mechanisms

D Schmidt, W Löscher - Epilepsia, 2005 - Wiley Online Library
Drug‐resistant epilepsy with uncontrolled severe seizures despite state‐of‐the‐art medical
treatment continues to be a major clinical problem for up to one in three patients with …

[HTML][HTML] Long-term mortality in childhood-onset epilepsy

M Sillanpää, S Shinnar - New England Journal of Medicine, 2010 - Mass Medical Soc
Background There are few studies on long-term mortality in prospectively followed, well-
characterized cohorts of children with epilepsy. We report on long-term mortality in a Finnish …

Natural history of treated childhood-onset epilepsy: prospective, long-term population-based study

M Sillanpää, D Schmidt - Brain, 2006 - academic.oup.com
It is not well known how often drug resistance, a major clinical problem, occurs early or late
in the course of epilepsy and how often epilepsy follows a continuous, remitting or relapsing …

Quantifying the response to antiepileptic drugs: effect of past treatment history

Y Schiller, Y Najjar - Neurology, 2008 - AAN Enterprises
Objective: To quantify the response to treatment with antiepileptic drugs (AEDs) as a function
of the past treatment history and identify additional prognostic factors for predicting the …

Update on the epidemiology and prognosis of pediatric epilepsy

S Shinnar, JM Pellock - Journal of Child Neurology, 2002 - journals.sagepub.com
Epilepsy is among the most common serious neurologic disorders in childhood.
Epidemiologic studies over the past few decades have greatly increased current knowledge …

Newly diagnosed unprovoked epileptic seizures: presentation at diagnosis in CAROLE study

P Jallon, P Loiseau, J Loiseau… - …, 2001 - Wiley Online Library
Purpose: We describe first unprovoked seizures and newly diagnosed epilepsies at initial
presentation, with a special emphasis on epilepsy syndromes, in a large cohort recruited in …

Double-blind placebo-controlled trial of adjunctive levetiracetam in pediatric partial seizures

TA Glauser, R Ayala, RD Elterman, WG Mitchell… - Neurology, 2006 - AAN Enterprises
Objective: To evaluate the efficacy and tolerability of levetiracetam (LEV) as adjunctive
therapy in children (4 to 16 years) with treatment-resistant partial-onset seizures. Methods …

Perceived impact of childhood‐onset epilepsy on quality of life as an adult

M Sillanpää, L Haataja, S Shinnar - Epilepsia, 2004 - Wiley Online Library
Purpose: Childhood‐onset epilepsy is a common disorder. The long‐term impact of having
childhood epilepsy on quality of life (QOL) as an adult, whether or not seizures are in …

Incidence of epilepsies and epileptic syndromes in children and adolescents: a population‐based prospective study in Germany

CM Freitag, TW May, M Pfäfflin, S König, D Rating - Epilepsia, 2001 - Wiley Online Library
Purpose: To estimate the incidence rate of epilepsies and epileptic syndromes in German
children and adolescents aged 1 month to< 15 years, and to provide data on their …