The mechanism of Leonuri Herba in improving polycystic ovary syndrome was analyzed based on network pharmacology and molecular docking
M Wu, H Liu, J Zhang, F Dai… - Journal of Pharmacy …, 2023 - frontierspartnerships.org
Background: Polycystic ovarian syndrome (PCOS) is the most common endocrine disorder
affecting women. Chinese herbs have been considered as an alternative treatment for …
affecting women. Chinese herbs have been considered as an alternative treatment for …
The inhibition of FTO attenuates the antifibrotic effect of leonurine in rat cardiac fibroblasts
Y Meng, T Xi, J Fan, Q Yang, J Ouyang… - … and Biophysical Research …, 2024 - Elsevier
Background Myocardial fibrosis (MF) is a common pathological condition in cardiovascular
diseases that often causes severe cardiac dysfunction. MF is characterized by changes in …
diseases that often causes severe cardiac dysfunction. MF is characterized by changes in …
A facile fluorescence-coupling approach to visualizing leonurine uptake and distribution in living cells and Caenorhabditis elegans
H Shi, J Yang, J Lin, X Hong, Z Zhou, J Zhao, Y Li, J Li… - Phytomedicine, 2024 - Elsevier
Background Caenorhabditis elegans (C. elegans) has been recognized for being a useful
model organism in small-molecule drug screens and drug efficacy investigation. However …
model organism in small-molecule drug screens and drug efficacy investigation. However …
Leonurine improves atherosclerosis by activating foam cell autophagy and metabolic remodeling via METTL3-mediated AKT1S1 mRNA stability modulation
X Yu, K Yin, J Wang, Y Zhang, X Wang, X Chen, X Zhu - Phytomedicine, 2024 - Elsevier
Background Atherosclerosis (AS) is the most prevalent cardiovascular disease and remains
the major contributor to death and mortality globally. Leonurine (LEO) is a unique alkaloid …
the major contributor to death and mortality globally. Leonurine (LEO) is a unique alkaloid …
The Chinese herbal prescription Kang-Gong-Yan alleviates cervicitis by modulating metabolites and gut microbiota
Y Zhao, M Yuan, X Sun, P Wang, X Meng… - Pharmaceutical …, 2024 - Taylor & Francis
Context Cervicitis is a common gynecological inflammatory disease. The Chinese herbal
prescription Kang-Gong-Yan (KGY) is clinically effective against cervicitis; however, the …
prescription Kang-Gong-Yan (KGY) is clinically effective against cervicitis; however, the …
[PDF][PDF] 益母草碱在炎症相关性疾病中作用的研究进展
熊佳伟， 马睿琦， 于华鹏， 牟林， 莫晓芬 - 复旦学报(医学版), 2024 - jms.fudan.edu.cn
益母草碱(leonurine, SCM-198) 是中药益母草(Herba Leonuri, HL) 活性成分之一,
现已能人工合成. 最新研究证实其在多种炎症相关性疾病动物模型中具有抗炎作用 …
现已能人工合成. 最新研究证实其在多种炎症相关性疾病动物模型中具有抗炎作用 …