Dizocilpine (MK‐801), an extensively investigated drug possessing secondary amine and
benzenoid functions, displays a wide array of biological properties, including anticonvulsant …

Introduction: Chronic orofacial pain is one of the most common pain conditions experienced
by adults. Animal models are often selected as the most useful scientific methodology to …

Orthodontic patients complain of pain for the first few days after insertion of appliances.
Mechanical force has been reported to produce oxidants in periodontal ligament (PDL) cells …

Orthodontic force produces mechanical irritation and inflammation in the periodontium,
which is inevitably accompanied by pain. Despite its prevalence, treatment of orthodontic …

Objective The aim of this study was to quantify the temporal changes in inflammation and
TRPA1, TRPV1 and CGRP expression in the trigeminal ganglion during force-induced …

Orthodontic force produces mechanical irritation and localized inflammation in the
periodontium, which causes pain in most patients. Nocifensive behaviors resulting from …

Background/Aim: The transient receptor potential vanilloid 1 (TRPV1) ion receptor is
involved in the release of calcitonin gene-related peptide (CGRP), a major contributor to …

To investigate whether transient receptor potential vanilloid type 1 (TRPV 1) is involved in
pain induced by experimental tooth movement, experiments were performed in male S …

Objective To examine the reliability of bite force for evaluating orthodontic tooth movement-
induced pain in rats. Design Orthodontic tooth movement-induced pain was induced by …

Background The pain caused by orthodontic treatment has been considered as tough
problems in orthodontic practice. Danggui-shaoyao-san (DSS) is a traditional Chinese …