Viral infections can give rise to a systemic decrease in the total number of lymphocytes in the
blood, referred to as lymphopenia. Lymphopenia may affect the host adaptive immune …

Background: There is increasing evidence that the presence of an ongoing systemic
inflammatory response is a stage-independent predictor of poor outcome in patients with …

Background Neutropenia increases the risk of infection, but it is unknown if this also applies
to lymphopenia. We therefore tested the hypotheses that lymphopenia is associated with …

Background: The immune system plays an important role in cancer surveillance and
therapy. Chemoradiation can cause severe treatment-related lymphopenia (TRL)(< 500 …

Abstract Purpose of Review Diabetic retinopathy (DR) is one of the most common
complications associated with chronic hyperglycemia seen in patients with diabetes mellitus …

Background The clinical value of the prognostic nutritional index (PNI) in gastric cancer (GC)
remains controversial. Therefore, we performed the meta-analysis to determine the …

Purpose The aim of this study was to investigate the impact of the prognostic nutritional
index (PNI) on the long-term outcomes in gastric cancer patients. Methods This study …

Background: The elevation of the platelet-to-lymphocyte ratio (PLR), an easily applicable
blood test based on platelet and lymphocyte counts has been associated with poor …

Cytotoxic chemotherapeutics (CCTs) are widely used in the treatment of cancer. Although
their mechanisms of action have been best understood in terms of targeting the apparatus of …

Purpose Emerging evidence suggests a detrimental prognostic association between
radiation-induced lymphopenia (RIL) and pathologic response, progression-free survival …