Purpose Nutrition and inflammation play a crucial role in the development of cancer. The
prognostic value of the prognostic nutritional index (PNI) has been confirmed in some types …

Blood cell counts often fail to report on immune processes occurring in remote tissues. Here,
we use immune cell type-specific methylation patterns in circulating cell-free DNA (cfDNA) …

Background Severe treatment‐related lymphopenia occurs commonly in many cancers and
is associated with early tumor progression. Data are lacking as to whether this occurs in …

BACKGROUND: Plasmablastic lymphoma (PBL) is a rare and aggressive B‐cell lymphoma
strongly associated with human immunodeficiency virus (HIV) infection. The authors …

Blockade of immune-checkpoints has emerged as one of the most promising approaches to
improve the durability of anti-tumor responses in cancer patients. However, the fraction of …

Background Radiation-related lymphopenia has been associated with suboptimal tumor
control rates leading to inferior survival outcomes. To date, no standardized dose constraints …

Background Low absolute lymphocyte count (ALC) has previously been established as a
marker of poor prognosis in multiple cancer types. There is growing evidence that ALC may …

Interleukin-7 (IL-7) is a non-hematopoietic cell-derived cytokine with a central role in the
adaptive immune system. It promotes lymphocyte development in the thymus and maintains …

Simple Summary Colorectal cancer (CRC) is one of the most common cancers worldwide.
Novel markers have been investigated in order to better predict the course of disease and …

Chemotherapy has historically been thought to induce cancer cell death in an
immunogenically silent manner. However, recent studies have demonstrated that …