Lung cancer in patients who have never smoked—An emerging disease
J LoPiccolo, A Gusev, DC Christiani… - Nature Reviews Clinical …, 2024 - nature.com
Lung cancer is the most common cause of cancer-related deaths globally. Although smoking-
related lung cancers continue to account for the majority of diagnoses, smoking rates have …
related lung cancers continue to account for the majority of diagnoses, smoking rates have …
Radon exposure: a major cause of lung cancer
M Lorenzo-Gonzalez, M Torres-Duran… - Expert review of …, 2019 - Taylor & Francis
Introduction: Lung cancer is the most important cause of cancer mortality. It is a multifactorial
disease with multiple risk factors, including residential radon exposure. Areas covered: The …
disease with multiple risk factors, including residential radon exposure. Areas covered: The …
A high frequency of sequence alterations is due to formalin fixation of archival specimens
C Williams, F Pontén, C Moberg, P Söderkvist… - The American journal of …, 1999 - Elsevier
Genomic analysis of archival tissues fixed in formalin is of fundamental importance in
biomedical research, and numerous studies have used such material. Although the …
biomedical research, and numerous studies have used such material. Although the …
Patterns of p53 G→ T transversions in lung cancers reflect the primary mutagenic signature of DNA-damage by tobacco smoke
P Hainaut, GP Pfeifer - Carcinogenesis, 2001 - academic.oup.com
It is unquestionable that the major cause of lung cancer is cigarette smoking. p53 mutations
are common in lung cancers from smokers but less common in non-smokers. A large fraction …
are common in lung cancers from smokers but less common in non-smokers. A large fraction …
[HTML][HTML] The cellular and molecular carcinogenic effects of radon exposure: a review
A Robertson, J Allen, R Laney, A Curnow - International journal of …, 2013 - mdpi.com
Radon-222 is a naturally occurring radioactive gas that is responsible for approximately half
of the human annual background radiation exposure globally. Chronic exposure to radon …
of the human annual background radiation exposure globally. Chronic exposure to radon …
Lung cancer in never smokers: molecular profiles and therapeutic implications
The majority of lung cancers are caused by long term exposure to the several classes of
carcinogens present in tobacco smoke. Although a significant fraction of lung cancers in …
carcinogens present in tobacco smoke. Although a significant fraction of lung cancers in …
Exposure to residential radon and lung cancer in Spain: a population-based case-control study
JM Barros-Dios, MA Barreiro… - American Journal of …, 2002 - academic.oup.com
Although high radon concentrations have been linked to increased risk of lung cancer by
both experimental studies and investigations of underground miners, epidemiologic studies …
both experimental studies and investigations of underground miners, epidemiologic studies …
Lung cancer risk and residential radon exposure: A pooling of case-control studies in northwestern Spain
M Lorenzo-Gonzalez, A Ruano-Ravina… - Environmental …, 2020 - Elsevier
Background Through a pooled case-control study design, we have assessed the
relationship between residential radon exposure and lung cancer risk. Other objectives of …
relationship between residential radon exposure and lung cancer risk. Other objectives of …
p53 and K-ras Mutations in Lung Cancers from Former and Never-Smoking Women
KH Vähäkangas, WP Bennett, K Castrén, JA Welsh… - Cancer research, 2001 - AACR
Somatic p53 mutations are common in lung cancer. Active cigarette smoking is positively
correlated with the total frequency of p53 mutations and G: C to T: A transversions on the …
correlated with the total frequency of p53 mutations and G: C to T: A transversions on the …
Residential radon exposure, histologic types, and lung cancer risk. A case–control study in Galicia, Spain
JM Barros-Dios, A Ruano-Ravina, M Perez-Rios… - … , biomarkers & prevention, 2012 - AACR
Background: Lung cancer is an important public health problem, and tobacco is the main
risk factor followed by residential radon exposure. Recommended exposure levels have …
risk factor followed by residential radon exposure. Recommended exposure levels have …