[HTML][HTML] Advances in oral drug delivery systems: Challenges and opportunities

J Lou, H Duan, Q Qin, Z Teng, F Gan, X Zhou, X Zhou - Pharmaceutics, 2023 - mdpi.com
The oral route is the most preferred route for systemic and local drug delivery. However, the
oral drug delivery system faces the harsh physiological and physicochemical environment of …

Ligand-modified nanocarriers for oral drug delivery: challenges, rational design, and applications

Y Zhang, Y Wang, X Li, D Nie, C Liu, Y Gan - Journal of Controlled Release, 2022 - Elsevier
Ligand-modified nanocarriers (LMNCs) specific to their targets have attracted increasing
interest for enhanced oral drug delivery in recent decades. Although the design of LMNCs …

[HTML][HTML] Improved synergistic anticancer action of quercetin and tamoxifen citrate supported by an electrospun complex nanostructure

J Li, Q Du, J Wan, DG Yu, F Tan, X Yang - Materials & Design, 2024 - Elsevier
A tri-fluid electrospinning process was successfully developed to prepare tri-chamber
complex nanofibers. The core–shell and Janus structure were combined to form a delicate …

Fucoidan/chitosan layered PLGA nanoparticles with melatonin loading for inducing intestinal absorption and addressing triple-negative breast cancer progression

YW Yen, YL Lee, LY Yu, CE Li, PW Shueng… - International Journal of …, 2023 - Elsevier
Melatonin and fucoidan are naturally active compounds that have been reported to have
therapeutic benefits for patients receiving cancer treatment. However, both compounds face …

[HTML][HTML] Anticancer nanotherapeutics in clinical trials: The work behind clinical translation of nanomedicine

A Parodi, EP Kolesova, MV Voronina… - International Journal of …, 2022 - mdpi.com
The ultimate goal of nanomedicine has always been the generation of translational
technologies that can ameliorate current therapies. Cancer disease represented the primary …

[HTML][HTML] Cracking the intestinal lymphatic system window utilizing oral delivery vehicles for precise therapy

YB Miao, T Xu, Y Gong, A Chen, L Zou, T Jiang… - Journal of …, 2023 - Springer
Oral administration is preferred over other drug delivery methods due to its safety, high
patient compliance, ease of ingestion without discomfort, and tolerance of a wide range of …

[HTML][HTML] Nanovesicles-mediated drug delivery for oral bioavailability enhancement

Y Ren, L Nie, S Zhu, X Zhang - International Journal of …, 2022 - ncbi.nlm.nih.gov
Bioavailability is an eternal topic that cannot be circumvented by peroral drug delivery.
Adequate blood drug exposure after oral administration is a prerequisite for effective …

[HTML][HTML] Interventional nanotheranostics in hepatocellular carcinoma

VP Chavda, PC Balar, SB Patel - Nanotheranostics, 2023 - ncbi.nlm.nih.gov
Interventional nanotheranostics is a system of drug delivery that does a dual function; along
with the therapeutic action, it also does have diagnostic features. This method helps in early …

Innovative nanotheranostics: Smart nanoparticles based approach to overcome breast cancer stem cells mediated chemo‐and radioresistances

P Kola, PKB Nagesh, PK Roy, K Deepak… - Wiley …, 2023 - Wiley Online Library
The alarming increase in the number of breast cancer patients worldwide and the increasing
death rate indicate that the traditional and current medicines are insufficient to fight against …

[HTML][HTML] Iridoid derivatives as anticancer agents: an updated review from 1970–2022

T Ndongwe, BA Witika, NP Mncwangi, MS Poka… - Cancers, 2023 - mdpi.com
Simple Summary Cancer is one of the leading causes of death around the world. The
current treatment strategies, especially chemotherapy, have significant side effects. As a …