Perspectives on the treatment of malignant pleural mesothelioma

SM Janes, D Alrifai, DA Fennell - New England Journal of …, 2021 - Mass Medical Soc
Mesothelioma Most mesotheliomas originate in the pleura and are due to asbestos
exposure. The incidence is decreasing somewhat with asbestos remediation, but mortality …

Biomarkers in the diagnosis of pleural diseases: a 2018 update

JM Porcel - Therapeutic advances in respiratory disease, 2018 - journals.sagepub.com
The use of biomarkers on pleural fluid (PF) specimens may assist the decision-making
process and enhance clinical diagnostic pathways. Three paradigmatic examples are heart …

British Thoracic Society guideline for pleural disease

ME Roberts, NM Rahman, NA Maskell, AC Bibby… - Thorax, 2023 - thorax.bmj.com
Conservative management can be considered for the treatment of minimally symptomatic
(ie, no significant pain or breathlessness and no physiological compromise) or …

Nivolumab or nivolumab plus ipilimumab in patients with relapsed malignant pleural mesothelioma (IFCT-1501 MAPS2): a multicentre, open-label, randomised, non …

A Scherpereel, J Mazieres, L Greillier… - The Lancet …, 2019 - thelancet.com
Background There is no recommended therapy for malignant pleural mesothelioma that has
progressed after first-line pemetrexed and platinum-based chemotherapy. Disease control …

ERS/ESTS/EACTS/ESTRO guidelines for the management of malignant pleural mesothelioma

A Scherpereel, I Opitz, T Berghmans… - European respiratory …, 2020 - Eur Respiratory Soc
The European Respiratory Society (ERS)/European Society of Thoracic Surgeons
(ESTS)/European Association for Cardio-Thoracic Surgery (EACTS)/European Society for …

[HTML][HTML] Update on biology and management of mesothelioma

R Asciak, V George, NM Rahman - European Respiratory …, 2021 - Eur Respiratory Soc
Malignant pleural mesothelioma is an aggressive, incurable cancer that is usually caused by
asbestos exposure several decades before symptoms arise. Despite widespread prohibition …

[HTML][HTML] Epidemiology and clinical aspects of malignant pleural mesothelioma

F Brims - Cancers, 2021 - mdpi.com
Simple Summary Mesothelioma is a cancer of the lining of the lungs caused by breathing in
asbestos fibres. Asbestos was widely used in industry in the last century in most developed …

[HTML][HTML] The immune microenvironment in mesothelioma: mechanisms of resistance to immunotherapy

GJ Chu, N Van Zandwijk, JEJ Rasko - Frontiers in Oncology, 2019 - frontiersin.org
Although mesothelioma is the consequence of a protracted immune response to asbestos
fibers and characterized by a clear immune infiltrate, novel immunotherapy approaches …

Malignant pleural effusion: diagnosis and management

L Ferreiro, J Suárez-Antelo… - Canadian …, 2020 - Wiley Online Library
Symptomatic malignant pleural effusion is a common clinical problem. This condition is
associated with very high mortality, with life expectancy ranging from 3 to 12 months. Studies …

[HTML][HTML] Pleural biomarkers in diagnostics of malignant pleural effusion: a narrative review

M Zhang, L Yan, G Lippi, ZD Hu - Translational lung cancer …, 2021 - ncbi.nlm.nih.gov
Although cytology and pleural biopsy of pleural effusion (PE) are the gold standards for
diagnosing malignant pleural effusion (MPE), these tools' diagnostic accuracy is plagued by …