Non-ionic surfactants for stabilization of polymeric nanoparticles for biomedical uses
H Cortés, H Hernández-Parra, SA Bernal-Chávez… - Materials, 2021 - mdpi.com
Surfactants are essential in the manufacture of polymeric nanoparticles by emulsion
formation methods and to preserve the stability of carriers in liquid media. The deposition of …
formation methods and to preserve the stability of carriers in liquid media. The deposition of …
Fucoidan in pharmaceutical formulations: a comprehensive review for smart drug delivery systems
Fucoidan is a heterogeneous group of polysaccharides isolated from marine organisms,
including brown algae and marine invertebrates. The physicochemical characteristics and …
including brown algae and marine invertebrates. The physicochemical characteristics and …
Integration of in vitro and in vivo models to predict cellular and tissue dosimetry of nanomaterials using physiologically based pharmacokinetic modeling
Nanomaterials (NMs) have been increasingly used in a number of areas, including
consumer products and nanomedicine. Target tissue dosimetry is important in the evaluation …
consumer products and nanomedicine. Target tissue dosimetry is important in the evaluation …
Coriander (Coriandrum sativum L.) essential oil and oil-loaded nano-formulations as an anti-aging potentiality via TGFβ/SMAD pathway
Aging has become a concern for many people, especially women. Given that high-quality
anti-aging products are of high cost; it has imperative to search for other economical …
anti-aging products are of high cost; it has imperative to search for other economical …
Chitosan surface-modified PLGA nanoparticles loaded with cranberry powder extract as a potential oral delivery platform for targeting colon cancer cells
Nutraceutical cranberry powder extract (CBPE) has distinct polyphenols inhibiting colon
cancer growth and proliferation. However, its oral therapeutic efficacy is hindered because …
cancer growth and proliferation. However, its oral therapeutic efficacy is hindered because …
pH-sensitive nanoparticles containing 5-fluorouracil and leucovorin as an improved anti-cancer option for colon cancer
Background: Parenteral administration of chemotherapeutic drugs, 5-fluorouracil (5-FU) and
leucovorin (LV), is commonly used to treat large bowel carcinomas such as colon cancer …
leucovorin (LV), is commonly used to treat large bowel carcinomas such as colon cancer …
Insights on development aspects of polymeric nanocarriers: the translation from bench to clinic
AK Tewari, SC Upadhyay, M Kumar, K Pathak… - Polymers, 2022 - mdpi.com
Scientists are focusing immense attention on polymeric nanocarriers as a prominent delivery
vehicle for several biomedical applications including diagnosis of diseases, delivery of …
vehicle for several biomedical applications including diagnosis of diseases, delivery of …
Repurposing of Guanabenz acetate by encapsulation into long-circulating nanopolymersomes for treatment of triple-negative breast cancer
Poor patient response and limited treatment modalities are the major challenges against
combating triple-negative breast cancer (TNBC). The high related mortality urges for novel …
combating triple-negative breast cancer (TNBC). The high related mortality urges for novel …
A comprehensive update of siRNA delivery design strategies for targeted and effective gene silencing in gene therapy and other applications
Introduction RNA interference (RNAi) using small interfering RNA (siRNA) is a promising
strategy to control many genetic disorders by targeting the mRNA of underlying genes and …
strategy to control many genetic disorders by targeting the mRNA of underlying genes and …
The idiosyncratic efficacy of spironolactone-loaded PLGA nanoparticles against murine intestinal schistosomiasis
Background Schistosomiasis is a chronic debilitating parasitic disease accompanied with
severe mortality rates. Although praziquantel (PZQ) acts as the sole drug for the …
severe mortality rates. Although praziquantel (PZQ) acts as the sole drug for the …