Autoinflammation and autoimmunity across rheumatic and musculoskeletal diseases
Z Szekanecz, IB McInnes, G Schett… - Nature Reviews …, 2021 - nature.com
Most rheumatic and musculoskeletal diseases (RMDs) can be placed along a spectrum of
disorders, with autoinflammatory diseases (including monogenic systemic autoinflammatory …
disorders, with autoinflammatory diseases (including monogenic systemic autoinflammatory …
Increased cardiovascular risk in rheumatoid arthritis: mechanisms and implications
Rheumatoid arthritis is a systemic autoimmune disease characterized by excess morbidity
and mortality from cardiovascular disease. Mechanisms linking rheumatoid arthritis and …
and mortality from cardiovascular disease. Mechanisms linking rheumatoid arthritis and …
Targeting protein modifications in metabolic diseases: molecular mechanisms and targeted therapies
The ever-increasing prevalence of noncommunicable diseases (NCDs) represents a major
public health burden worldwide. The most common form of NCD is metabolic diseases …
public health burden worldwide. The most common form of NCD is metabolic diseases …
Extracellular matrix dynamics in vascular remodeling
Z Ma, C Mao, Y Jia, Y Fu… - American Journal of …, 2020 - journals.physiology.org
Vascular remodeling is the adaptive response to various physiological and
pathophysiological alterations that are closely related to aging and vascular diseases …
pathophysiological alterations that are closely related to aging and vascular diseases …
Extra-articular rheumatoid arthritis
E Marcucci, E Bartoloni, A Alunno, MC Leone, G Cafaro… - 2018 - reumatismo.org
Rheumatoid arthritis (RA) is a chronic inflammatory disease that mainly affects the joints,
though a consistent proportion of patients may also display extra articular manifestations …
though a consistent proportion of patients may also display extra articular manifestations …
The Porphyromonas gingivalis/Host Interactome Shows Enrichment in GWASdb Genes Related to Alzheimer's Disease, Diabetes and Cardiovascular Diseases
Periodontal disease is of established etiology in which polymicrobial synergistic ecology has
become dysbiotic under the influence of Porphyromonas gingivalis. Following breakdown of …
become dysbiotic under the influence of Porphyromonas gingivalis. Following breakdown of …
Oxidative stress-mediated alterations in histone post-translational modifications
JL García-Giménez, C Garcés, C Romá-Mateo… - Free Radical Biology …, 2021 - Elsevier
Epigenetic regulation of gene expression provides a finely tuned response capacity for cells
when undergoing environmental changes. However, in the context of human physiology or …
when undergoing environmental changes. However, in the context of human physiology or …
Citrullination as a plausible link to periodontitis, rheumatoid arthritis, atherosclerosis and Alzheimer's disease
I Olsen, SK Singhrao, J Potempa - Journal of oral microbiology, 2018 - Taylor & Francis
ABSTRACT Periodontitis, rheumatoid arthritis (RA), atherosclerosis (AS), and Alzheimer's
disease (AD) are examples of complex human diseases with chronic inflammatory …
disease (AD) are examples of complex human diseases with chronic inflammatory …
Innate and adaptive immunity in cardiovascular calcification
Despite the focus placed on cardiovascular research, the prevalence of vascular and
valvular calcification is increasing and remains a leading contributor of cardiovascular …
valvular calcification is increasing and remains a leading contributor of cardiovascular …
Atherosclerosis in rheumatoid arthritis: promoters and opponents
Substantial epidemiological data identified cardiovascular (CV) diseases as a main cause of
mortality in patients with rheumatoid arthritis (RA). In light of this, RA patients may benefit …
mortality in patients with rheumatoid arthritis (RA). In light of this, RA patients may benefit …