Over the course of the last century, organ transplantation has overcome major technical
limitations to become the success it is today. The breakthroughs include developing …

Biomaterials: Principles and Applications offers a comprehensive review of all the major
biomaterials in this rapidly growing field. In recent years, the role of biomaterials has been …

The development of methods to safely preserve organs retrieved from victims of life-ending
accidents greatly improved the versatility of human organ transplantation. In fact, the …

Experiments were carried out on 15 human descending thoracic aortas from heart-beating
healthy donors who donated organs for transplant. The aortas were kept refrigerated in …

I SCHEMIC and hypoxic liver injury are caused by absolute and relative deficiency of
oxygen, respectively. Ischemic liver injury occurs during storage of livers for transplantation …

Background. Major causes of death after heart transplantation are right ventricular pump
failure and, chronically, cardiac allograft vasculopathy. Traditional preservation techniques …

Renal transplantation is the preferred treatment for end-stage renal disease. Currently, there
is a large gap between the supply and demand for transplantable kidneys. The use of sub …

Intestinal ischemia-reperfusion injury (IRI) is a common clinical entity, and its outcome is
unpredictable due to the triad of inflammation, increased permeability and bacterial …

Functional studies on isolated mitochondria critically rely on the right choice of respiration
buffer. Differences in buffer composition can lead to dramatically different respiration rates …

Abstract Machine perfusion (MP) is at the forefront of innovation in modern liver
transplantation. Several approaches, mainly varying the temperature at which the graft is …