Neurofluids is a term introduced to define all fluids in the brain and spine such as blood,
cerebrospinal fluid, and interstitial fluid. Neuroscientists in the past millennium have steadily …

The comprehension of the glymphatic system, a postulated mechanism responsible for the
removal of interstitial solutes within the central nervous system (CNS), has witnessed …

Objective The glymphatic system cleans amyloid and tau proteins from the brain in animal
studies of Alzheimer disease (AD). However, there is no direct evidence showing this in …

Background Brain glymphatic dysfunction may contribute to the development of α-
synucleinopathies. Yet, noninvasive imaging and quantification remain lacking. Purpose To …

Background Alzheimer's disease (AD) pathology impairs cognitive function. Yet some
individuals with high amounts of AD pathology suffer marked memory impairment, while …

Objective This study aims to investigate the associations of glymphatic system with the
presence, severity and neuroimaging phenotypes of cerebral small vessel disease (CSVD) …

Objective Choroid plexus (CP) is a key regulator in cerebrospinal fluid production, but its
contribution to glymphatic clearance function and association with white matter …

Objective The glymphatic system is a glial-based perivascular network that promotes brain
metabolic waste clearance. Reduced glymphatic flow has been observed in rat models of …

Background and Objectives The glymphatic system is a whole-brain perivascular network,
which promotes CSF/interstitial fluid exchange. Alterations to this system may play a pivotal …

The importance of the perivascular space (PVS) as one of the imaging markers of cerebral
small vessel disease (CSVD) has been widely appreciated by the neuroradiologists. The …