Choroid plexus enlargement exacerbates white matter hyperintensity growth through glymphatic impairment
Y Li, Y Zhou, W Zhong, X Zhu, Y Chen… - Annals of …, 2023 - Wiley Online Library
Objective Choroid plexus (CP) is a key regulator in cerebrospinal fluid production, but its
contribution to glymphatic clearance function and association with white matter …
contribution to glymphatic clearance function and association with white matter …
Gray matter reserve determines glymphatic system function in young‐onset Alzheimer's disease: evidenced by DTI‐ALPS and compared with age‐matched controls
HI Chang, CW Huang, SW Hsu… - Psychiatry and …, 2023 - Wiley Online Library
Background The diffusion tensor imaging analysis along the perivascular space (ALPS)‐
index can be used to model the glymphatic system in vivo. Aim This study explores putative …
index can be used to model the glymphatic system in vivo. Aim This study explores putative …
Association of cognition and brain reserve in aging and glymphatic function using diffusion tensor image-along the perivascular space (DTI-ALPS)
WC Hsiao, HI Chang, SW Hsu, CC Lee, SH Huang… - Neuroscience, 2023 - Elsevier
The glymphatic system is a fluid-clearance pathway that clears cerebral waste products, and
its dysfunction has been associated with protein aggregation diseases such as Alzheimer's …
its dysfunction has been associated with protein aggregation diseases such as Alzheimer's …
Noninvasive magnetic resonance imaging measures of glymphatic system activity
K Kamagata, Y Saito, C Andica… - Journal of Magnetic …, 2024 - Wiley Online Library
The comprehension of the glymphatic system, a postulated mechanism responsible for the
removal of interstitial solutes within the central nervous system (CNS), has witnessed …
removal of interstitial solutes within the central nervous system (CNS), has witnessed …
Diffusion-weighted image analysis along the perivascular space (DWI–ALPS) for evaluating interstitial fluid status: age dependence in normal subjects
Purpose The purpose of this study was to evaluate the interstitial fluid status in a wide range
of age groups using diffusion-weighted image analysis along the perivascular space (DWI …
of age groups using diffusion-weighted image analysis along the perivascular space (DWI …
Glymphatic system impairment in sleep disruption: diffusion tensor image analysis along the perivascular space (DTI-ALPS)
Y Saito, Y Hayakawa, K Kamagata, J Kikuta… - Japanese Journal of …, 2023 - Springer
Purpose This study aimed to evaluate the relationship between sleep quality as assessed
using the Pittsburgh Sleep Quality Index (PSQI) and the index of diffusivity along the …
using the Pittsburgh Sleep Quality Index (PSQI) and the index of diffusivity along the …
DTI-ALPS: An MR biomarker for motor dysfunction in patients with subacute ischemic stroke
Y Qin, X Li, Y Qiao, H Zou, Y Qian, X Li, Y Zhu… - Frontiers in …, 2023 - frontiersin.org
Purpose Brain glymphatic dysfunction is involved in the pathologic process of acute
ischemic stroke (IS). The relationship between brain glymphatic activity and dysfunction in …
ischemic stroke (IS). The relationship between brain glymphatic activity and dysfunction in …
Interstitial fluidopathy of the central nervous system: an umbrella term for disorders with impaired neurofluid dynamics
Interest in interstitial fluid dynamics has increased since the proposal of the glymphatic
system hypothesis. Abnormal dynamics of the interstitial fluid have been pointed out to be an …
system hypothesis. Abnormal dynamics of the interstitial fluid have been pointed out to be an …
Vascular risk factors and astrocytic marker for the glymphatic system activity
Objectives Glymphatic system maintains brain fluid circulation via active transportation of
astrocytic aquaporin-4 in perivascular space. The diffusion tensor imaging analysis along …
astrocytic aquaporin-4 in perivascular space. The diffusion tensor imaging analysis along …
Glymphatic dysfunction mediates the influence of white matter hyperintensities on episodic memory in cerebral small vessel disease
Z Ke, Y Mo, J Li, D Yang, L Huang, Z Yang, R Qin… - Brain Sciences, 2022 - mdpi.com
Glymphatic dysfunction has been linked to cognitive decline in several neurodegenerative
diseases. In cerebral small vessel disease (CSVD), the mechanism of white matter …
diseases. In cerebral small vessel disease (CSVD), the mechanism of white matter …