Effects of exposure to the explosive and environmental pollutant 2, 4, 6-trinitrotoluene on ovarian follicle development in rats

D Lin, Y Chen, L Liang, Z Huang, Y Guo, P Cai… - … Science and Pollution …, 2023 - Springer
Abstract Although 2, 4, 6-trinitrotoluene (TNT) is a dangerous carcinogen in environmental
pollution, information on the reproductive effects of TNT explosive contamination is limited …

[HTML][HTML] Chemerin: a functional adipokine in reproductive health and diseases

M Yu, Y Yang, C Huang, L Ge, L Xue, Z Xiao, T Xiao… - Biomedicines, 2022 - mdpi.com
As a multifaceted adipokine, chemerin has been found to perform functions vital for
immunity, adiposity, and metabolism through its three known receptors (chemokine-like …

[HTML][HTML] The differential roles for neurodevelopmental and neuroendocrine genes in shaping GnRH neuron physiology and deficiency

R Oleari, V Massa, A Cariboni, A Lettieri - International Journal of …, 2021 - mdpi.com
Gonadotropin releasing hormone (GnRH) neurons are hypothalamic neuroendocrine cells
that control sexual reproduction. During embryonic development, GnRH neurons migrate …

A comprehensive review of the new FIGO classification of ovulatory disorders

AH Balen, J Tamblyn, K Skorupskaite… - Human Reproduction …, 2024 - academic.oup.com
Abstract BACKGROUND The World Health Organization (WHO) system for the classification
of disorders of ovulation was produced 50 years ago and, by international consensus, has …

Circadian clock gene BMAL1 controls testosterone production by regulating steroidogenesis‐related gene transcription in goat Leydig cells

Y Xiao, L Zhao, W Li, X Wang, T Ma… - Journal of Cellular …, 2021 - Wiley Online Library
Testosterone is produced by Leydig cells (LCs) and undergoes diurnal changes in serum
levels in rats, mice, and humans, but little is known in goats. The present study revealed that …

Behavioral disorders caused by nonylphenol and strategies for protection

D Lu, L Yu, M Li, Q Zhai, F Tian, W Chen - Chemosphere, 2021 - Elsevier
Nonylphenol (NP) is widely used in daily production and life due to its good emulsification.
In this review, we discuss toxicology studies that examined behavioral disorders caused by …

A framework for high-resolution phenotyping of candidate male infertility mutants: from human to mouse

BJ Houston, DF Conrad, MK O'Bryan - Human genetics, 2021 - Springer
Male infertility is a heterogeneous condition of largely unknown etiology that affects at least
7% of men worldwide. Classical genetic approaches and emerging next-generation …

Applying the adverse outcome pathway concept for assessing non-monotonic dose responses: Biphasic effect of bis (2-ethylhexyl) phthalate (DEHP) on testosterone …

MC Astuto, D Benford, L Bodin, I Cattaneo… - Archives of …, 2023 - Springer
Male reproduction is one of the primary health endpoints identified in rodent studies for
some phthalates, such as DEHP (Bis (2-ethylhexyl) phthalate), DBP (Dibutyl phthalate), and …

[HTML][HTML] Effects of melatonin on anterior pituitary plasticity: a comparison between mammals and teleosts

E Ciani, TM Haug, G Maugars, FA Weltzien… - Frontiers in …, 2021 - frontiersin.org
Melatonin is a key hormone involved in the photoperiodic signaling pathway. In both teleosts
and mammals, melatonin produced in the pineal gland at night is released into the blood …

[HTML][HTML] Gonads under stress: A systematic review and meta-analysis on the effects of acute psychosocial stress on gonadal steroids secretion in humans

G Domes, K Linnig, B von Dawans - Psychoneuroendocrinology, 2024 - Elsevier
Animal research has shown that the hypothalamus-pituitary-gonadal (HPG) axis is inhibited
by (chronic and/or severe) stress, which can lead to impaired fertility and reproductive …