[HTML][HTML] Therapeutic dosing and targeting efficacy of Pt-Mal-LHRH towards triple negative breast cancer

M Ndinguri, L Middleton, J Unrine, S Lui, J Rollins… - Plos one, 2023 - journals.plos.org
Objective Pt-Mal-LHRH is a newly synthesized chemotherapeutic agent that was designed
to selectively target the luteinizing hormone-releasing hormone (LHRH) receptor expressed …

Endocrine disrupting chemicals (EDCs) and the neuroendocrine system: Beyond estrogen, androgen, and thyroid

HB Patisaul - Advances in Pharmacology, 2021 - Elsevier
Hundreds of anthropogenic chemicals occupy our bodies, a situation that threatens the
health of present and future generations. This chapter focuses on endocrine disrupting …

环境内分泌干扰物影响垂体促性腺激素的研究进展.

刘晓晨, 刘璟 - Asian Journals of Ecotoxicology, 2022 - search.ebscohost.com
通过工业和农业生产活动排入环境的多种农药, 阻燃剂, 多氯联苯, 塑料包装成分, 防腐剂,
工业副产物, 重金属等化学物质, 已被证明是内分泌干扰物(endocrine-disrupting chemicals …

[HTML][HTML] Restorative functions of Autologous Stem Leydig Cell transplantation in a Testosterone-deficient non-human primate model

K Xia, H Chen, J Wang, X Feng, Y Gao, Y Wang… - Theranostics, 2020 - ncbi.nlm.nih.gov
Abstract Rationale: Stem Leydig cells (SLCs) transplantation can restore testosterone
production in rodent models and is thus a potential solution for treating testosterone …

The Gn RH analogues affect novel neuropeptide SMIM 20/phoenixin and GPR 173 receptor expressions in the female rat hypothalamic–pituitary–gonadal (HPG) axis

A Suszka‐Świtek, A Pałasz, Ł Filipczyk… - Clinical and …, 2019 - Wiley Online Library
The recently discovered peptide phoenixin (PNX) and its receptor GPR 173 are novel factors
that exhibit a large spectrum of regulatory activity, especially when considered as a central …

Prenatal exposure to the phthalate DEHP impacts reproduction-related gene expression in the pituitary

X Ge, K Weis, J Flaws, L Raetzman - Reproductive Toxicology, 2022 - Elsevier
Phthalates are chemicals used in products including plastics, personal care products, and
building materials, leading to widespread contact. Previous studies on prenatal exposure to …

Prepubertal exposure to polycyclic aromatic hydrocarbons are associated with early pubertal development onset in boys: A longitudinal study

Y Wang, W Wu, MA Bravo, S Liu, X Xi, Y Zhou… - Journal of Hazardous …, 2024 - Elsevier
Objective To investigate the effects of polycyclic aromatic hydrocarbons (PAHs) on puberty
in boys. Methods 695 subjects were selected from four primary schools in Chongqing …

[HTML][HTML] 11-oxygenated androgens and their relation to hypothalamus-pituitary-gonadal-axis disturbances in adults with congenital adrenal hyperplasia

MK Auer, L Paizoni, M Neuner, C Lottspeich… - The Journal of Steroid …, 2021 - Elsevier
Context Hypothalamus-pituitary-gonadal (HPG)-axis disturbances are a common
phenomenon in patients with classic congenital adrenal hyperplasia (CAH). 11-oxygenated …

[HTML][HTML] A Testis-Specific Long Noncoding RNA, Start, Is a Regulator of Steroidogenesis in Mouse Leydig Cells

K Otsuka, S Matsubara, A Shiraishi, N Takei… - Frontiers in …, 2021 - frontiersin.org
The testis expresses many long noncoding RNAs (lncRNAs), but their functions and
overview of lncRNA variety are not well understood. The mouse Prss/Tessp locus contains …

Neuropeptides and hormones in hypothalamus-pituitary axis of Chinese sturgeon (Acipenser sinensis)

Y Xie, K Xiao, T Cai, X Shi, L Zhou, H Du, J Yang… - General and …, 2023 - Elsevier
The hypothalamus and pituitary serve as important neuroendocrine center, which is able to
secrete a variety of neuropeptides and hormones to participate in the regulation of …