This review article focuses on the research progress made in the structural modifications of
camptothecin (CPT), a potent cytotoxic natural alkaloid. CPT possesses a unique 5-fused …

Fungi that spoil foods or infect crops can have major socioeconomic impacts, posing threats
to food security. The strategies needed to manage these fungi are evolving, given the …

Plant diseases caused by phytopathogenic fungi reduce the yield and quality of crops. To
develop novel antifungal agents, we designed and synthesized eight series of …

Eugenol, the generic name of 4-allyl-2-methoxyphenol, is the major component of clove
essential oil, and has demonstrated relevant biological potential with well-known …

Derivatives of morpholine are biologically active organic compounds with special structures
discovered in multiple drugs. As a result of the terminal pharmacophore of action and …

Developing novel fungicide candidates are intensively promoted by the rapid emergences of
resistant fungi that outbreak on agricultural production. Aiming to discovery novel antifungal …

Crop diseases caused by fungi threaten food security and exacerbate the food crisis.
Inspired by the application of fungicide candidates from natural products in agrochemical …

Plant pathogenic fungi seriously threaten agricultural production. There is an urgent need to
develop novel fungicides with low toxicity and high efficiency. In this study, we designed and …

In order to increase the application of natural bioresources in drug discovery and
development, a study on N-acetyl-glucosamine (GlcNAc) derivatives of chitin as green …

The use of cyclodextrins as drug nano-carrier systems for drug delivery is gaining
importance in the pharmaceutical industry due to the interesting pharmacokinetic properties …