Copper (Cu) is a vital mineral essential for many biological processes. The vast majority of
all Cu in healthy humans is associated with enzyme prosthetic groups or bound to proteins …

Oxidative stress has long been implicated in cardiovascular disease, but more recently, the
role of reactive oxygen species (ROS) in normal physiological signaling has been …

COVID-19, the disease caused by the novel Coronavirus, SARS-CoV-2, is increasingly
being recognized as a systemic thrombotic and microvascular injury syndrome that may …

Copper is an essential micronutrient for human body and plays a vital role in various
biological processes including cellular respiration and free radical detoxification. Generally …

Copper (Cu) is an integral part of many important enzymes involved in a number of vital
biological processes. Although normally bound to proteins, Cu may be released and …

Copper (Cu), a redox active metal, is an essential nutrient for all species studied to date.
During the past decade, there has been increasing interest in the concept that marginal …

Background—Impaired flow-dependent, endothelium-mediated vasodilation (FDD) in
patients with chronic heart failure (CHF) results, at least in part, from accelerated …

Zinc (Zn) and copper (Cu) are essential microelements, which take part in cellular
metabolism, feature in enzymatic systems, and regulate enzyme activity. Homeostasis of …

In this review we consider the effects of endogenous and pharmacological levels of nitrite
under conditions of hypoxia. In humans, the nitrite anion has long been considered as …

The evanescent nature of reactive oxygen and nitrogen species, the multiple cellular
mechanisms evolved to maintain these substances at low (submicromolar) concentrations …