The asymmetric alkylation of enolates is a particularly versatile method for the construction
of α-stereogenic carbonyl motifs, which are ubiquitous in synthetic chemistry. Over the past …

Electrochemistry has emerged as a powerful means to enable redox transformations in
modern chemical synthesis. This tutorial review delves into the unique advantages of …

The preparation of both enantiomers of chiral molecules is among the most fundamental
tasks in organic synthesis, medicinal chemistry and materials science. Achieving this goal …

Sharpless asymmetric dihydroxylation is an important reaction in the enantioselective
synthesis of chiral vicinal diols that involves the treatment of alkene with osmium tetroxide …

A robust system for the preparation of β-heteroaryl α-amino acid derivatives has been
developed using photoredox catalysis. This system operates via regiospecific activation of …

Catenanes, molecules in which two rings are threaded through one another like links in a
chain, can form as two structures related like an object and its mirror image but otherwise …

The targeted synthesis of a desired stereomer plays a key role in life sciences, especially in
the production of drugs. Up to date, this area is dominated by homogeneous chiral catalysts …

Herein, we reported an intermolecular asymmetric hydrative aldol reaction through vinyl‐
gold intermediate under ambient conditions. This tandem alkyne hydration and sequential …

Imines can be reduced to afford synthetically important amines via a number of means, of
which half-sandwich metal complex-effected reduction has gained particular prominence in …

A site-selective alkylation of dehydroalanine to access protected unnatural amino acids is
described. The protocol is characterized by the wide nature of alkyl radicals employed, mild …