Pathophysiology of atherosclerosis

S Jebari-Benslaiman, U Galicia-García… - International journal of …, 2022 - mdpi.com
Atherosclerosis is the main risk factor for cardiovascular disease (CVD), which is the leading
cause of mortality worldwide. Atherosclerosis is initiated by endothelium activation and …

COVID-19 is, in the end, an endothelial disease

P Libby, T Lüscher - European heart journal, 2020 - academic.oup.com
The vascular endothelium provides the crucial interface between the blood compartment
and tissues, and displays a series of remarkable properties that normally maintain …

Intravascular mesenchymal stromal/stem cell therapy product diversification: time for new clinical guidelines

G Moll, JA Ankrum, J Kamhieh-Milz, K Bieback… - Trends in molecular …, 2019 - cell.com
Intravascular infusion is the most popular route for therapeutic multipotent mesenchymal
stromal/stem cell (MSC) delivery in hundreds of clinical trials. Meta-analysis has …

Endothelial dysfunction and hypertension

D Konukoglu, H Uzun - Hypertension: from basic research to clinical …, 2017 - Springer
In the past, endothelium was thought to be only a mechanical barrier. Today, endothelium is
known to be a tissue regulating vascular tone, cell growth and the interaction between the …

Risk of bleeding with 2 doses of dabigatran compared with warfarin in older and younger patients with atrial fibrillation: an analysis of the randomized evaluation of …

JW Eikelboom, L Wallentin, SJ Connolly, M Ezekowitz… - Circulation, 2011 - Am Heart Assoc
Background—Dabigatran 150 and 110 mg twice a day and warfarin are effective for stroke
prevention in atrial fibrillation. The purpose of this study was to compare their risks of …

Triglyceride-rich lipoproteins as a causal factor for cardiovascular disease

PP Toth - Vascular health and risk management, 2016 - Taylor & Francis
Approximately 25% of US adults are estimated to have hypertriglyceridemia (triglyceride
[TG] level≥ 150 mg/dL [≥ 1.7 mmol/L]). Elevated TG levels are associated with increased …

Drug-eluting stent and coronary thrombosis: biological mechanisms and clinical implications

TF Lüscher, J Steffel, FR Eberli, M Joner… - Circulation, 2007 - Am Heart Assoc
Although rare, stent thrombosis remains a severe complication after stent implantation owing
to its high morbidity and mortality. Since the introduction of drug-eluting stents (DES), most …

Vascular responses to drug eluting stents: importance of delayed healing

AV Finn, G Nakazawa, M Joner… - … , and vascular biology, 2007 - Am Heart Assoc
Polymer-based sirolimus-(Cypher) and paclitaxel-eluting (Taxus) drug eluting stents have
become the treatment of choice for patients with symptomatic coronary artery disease …

[HTML][HTML] The role of saliva in tick feeding

IMB Francischetti, A Sa-Nunes, BJ Mans… - … in bioscience: a …, 2009 - ncbi.nlm.nih.gov
When attempting to feed on their hosts, ticks face the problem of host hemostasis (the
vertebrate mechanisms that prevent blood loss), inflammation (that can produce itching or …

Vascular endothelial tissue factor contributes to trimethylamine N-oxide-enhanced arterial thrombosis

M Witkowski, M Witkowski, J Friebel… - Cardiovascular …, 2022 - academic.oup.com
Aims Gut microbiota and their generated metabolites impact the host vascular phenotype.
The metaorganismal metabolite trimethylamine N-oxide (TMAO) is both associated with …