Background and aims Alcohol use is a major contributor to injuries, mortality and the burden
of disease. This review updates knowledge on risk relations between dimensions of alcohol …

Executive summary Alzheimer's disease (AD) is the leading cause of dementia, and
because the primary risk factor for AD is old age, the prevalence of the disease is increasing …

Importance Genetic factors increase risk of dementia, but the extent to which this can be
offset by lifestyle factors is unknown. Objective To investigate whether a healthy lifestyle is …

An estimated 47 million people worldwide are living with dementia in 2015, and this number
is projected to triple by 2050. In the absence of a disease-modifying treatment or cure …

Background Alcohol use has been identified as a risk factor for dementia and cognitive
decline. However, some patterns of drinking have been associated with beneficial effects …

Objective To examine the association between alcohol consumption and risk of dementia.
Design Prospective cohort study. Setting Civil service departments in London (Whitehall II …

Objectives To investigate whether moderate alcohol consumption has a favourable or
adverse association or no association with brain structure and function. Design …

Background Methamphetamine has long been considered as a neurotoxic substance
causing cognitive deficits. Recently, however, the magnitude and the clinical significance of …

A systematic review was conducted to identify risk factors associated with the onset and
progression of Alzheimer's disease (AD). Moderate and high quality systematic reviews …

Objective Dementia has a multifactorial etiology, but the importance of individual health and
lifestyle related risk factors is often uncertain or based on few studies. The goal of this paper …