Measurement error and timing of predictor values for multivariable risk prediction models are poorly reported

R Whittle, G Peat, J Belcher, GS Collins… - Journal of clinical …, 2018 - Elsevier
Objective Measurement error in predictor variables may threaten the validity of clinical
prediction models. We sought to evaluate the possible extent of the problem. A secondary …

Role of total tumour load of sentinel lymph node on survival in early breast cancer patients

V Peg, I Sansano, B Vieites, L Bernet, R Cano… - The Breast, 2017 - Elsevier
Background Axillary staging (pN) is considered one of the most important prognostic factors
in breast cancer patients. However, the Z0011 study data drastically reduced the number of …

Evaluation of fast molecular detection of lymph node metastases in prostate cancer patients using one-step nucleic acid amplification (OSNA)

S Engels, L Brautmeier, L Reinhardt, C Wasylow… - Cancers, 2021 - mdpi.com
Simple Summary Prostate cancer (PCa) is the second most common cancer and one of the
highestcauses of cancer deaths among men. The presence of lymph node metastases …

A new prediction nomogram of non-sentinel lymph node metastasis in cT1-2 breast cancer patients with positive sentinel lymph nodes

L Yang, X Zhao, L Yang, Y Chang, C Cao, X Li… - Scientific Reports, 2024 - nature.com
We aimed to analyze the risk factors and construct a new nomogram to predict non-sentinel
lymph node (NSLN) metastasis for cT1-2 breast cancer patients with positivity after sentinel …

Construction and validation of a risk prediction model for clinical axillary lymph node metastasis in T1–2 breast cancer

N Luo, Y Wen, Q Zou, D Ouyang, Q Chen, L Zeng… - Scientific Reports, 2022 - nature.com
The current diagnostic technologies for assessing the axillary lymph node metastasis
(ALNM) status accurately in breast cancer (BC) remain unsatisfactory. Here, we developed a …

Intraoperative prediction of the two axillary lymph node macrometastases threshold in patients with breast cancer using a one‑step nucleic acid cytokeratin‑19 …

V Fung, S Kohlhardt, P Vergani… - Molecular and …, 2017 - spandidos-publications.com
The aim of the present study was to assess the sensitivity, specificity and practicality of using
a one‑step nucleic acid amplification (OSNA) assay during breast cancer staging surgery to …

External validation of a prognostic model based on total tumor load of sentinel lymph node for early breast cancer patients

A Piñero-Madrona, F Ripoll-Orts… - Breast Cancer Research …, 2020 - Springer
Background A prognostic model based on the results of molecular analysis of sentinel lymph
nodes (SLN) is needed to replace the information that staging the entire axilla provided. The …

Sentinel node total tumour load as a predictive factor for non-sentinel node status in early breast cancer patients–The porttle study

JL Fougo, I Amendoeira, MJ Brito, AP Correia… - Surgical Oncology, 2020 - Elsevier
OSNA is a molecular assay for the detection of sentinel node metastasis. TTL emerged as a
concept that seems to accurately predict the status of the NSN. Authors tried to confirm this …

A cut-off of 2150 cytokeratin 19 mRNA copy number in sentinel lymph node may be a powerful predictor of non-sentinel lymph node status in breast cancer patients

I Terrenato, V D'Alicandro, B Casini, L Perracchio… - PLoS …, 2017 - journals.plos.org
Since 2007, one-step nucleic acid amplification (OSNA) has been used as a diagnostic
system for sentinel lymph node (SLN) examination in patients with breast cancer. This study …

[HTML][HTML] Detection of CK19 mRNA using one-step nucleic acid amplification (OSNA) in prostate Cancer: preliminary results

A Winter, S Engels, P Goos, MC Süykers… - Journal of …, 2018 - ncbi.nlm.nih.gov
Background: Accurate histopathological evaluation of lymph nodes (LNs) is essential for
reliable staging in prostate cancer. In routine practice, conventional techniques only …