Purpose: Previous conflicting results about the prognostic significance of estrogen receptor
(ER)-β in breast cancer may be explained by contribution of isoforms, of which five exist. Our …

Thyroid cancer occurs three times more frequently in females than in males, and in females
the incidence decreases after menopause. This gender difference suggests that the growth …

This review emphasizes the relationship of breast cancer, estrogen receptor and ligands,
especially the centrality of the estrogen receptor, which mediates on one hand the hormone …

Aim: Two oestrogen receptors (ERs) have been identified to date—the “classic” ERα and the
more recently described ERβ. Although much is known about ERα at the mRNA and protein …

Ovarian cancer is one of the leading causes of death from gynecological tumors in women.
Several lines of evidence suggest that estrogens may play an important role in ovarian …

Estrogen, in the clinical setting is used primarily for contraception and hormone replacement
therapy. It has been well established that estrogen increases the risk of both arterial and …

More than 10 years have passed since the discovery of the second estrogen receptor,
estrogen receptor β (ERβ). It is now evident that ERα is not the only ER in breast cancer …

The allele frequencies of three restriction fragment length polymorphisms at the oestrogen
receptor (ESR) locus were compared between breast cancer patients and controls …

Endocrine therapy is currently the main therapeutic approach for estrogen receptor-positive
(ER+) breast cancer, the most frequent subtype of breast cancer in women worldwide. For …

Endometrial polyps are a frequent cause of abnormal uterine bleeding, but their
pathogenesis is poorly understood. This study was undertaken to investigate if endometrial …