The Estrogen Receptor CpG Island Is Methylated in Most Hematopoietic Neoplasms

JPJ Issa, BA Zehnbauer, CI Civin, MI Collector… - Cancer research, 1996 - AACR
Estrogen appears to be a negative regulator of normal hematopoiesis, Chromosome 6q,
which contains the estrogen receptor (ER) gene, is frequently altered in human …

Analysis of estrogen-and progesterone-receptor expression in endometrial polyps

RGC Lopes, EC Baracat… - Journal of minimally …, 2007 - Elsevier
STUDY OBJECTIVE: To investigate the presence of estrogen receptors (ER) and
progesterone receptors (PR) in the glandular epithelium and stroma of endometrial polyps in …

Frequent methylation of estrogen receptor in prostate cancer: correlation with tumor progression

LC Li, R Chui, K Nakajima, BR Oh, HC Au, R Dahiya - Cancer research, 2000 - AACR
Prior studies have shown that the estrogen receptor (ER) gene is down-regulated in prostate
cancer, but the mechanism of its inactivation is not known. We hypothesize that inactivation …

Genetic polymorphisms in the estrogen receptor α gene and risk of breast cancer: results from the Shanghai Breast Cancer Study

Q Cai, XO Shu, F Jin, Q Dai, W Wen, JR Cheng… - … Biomarkers & Prevention, 2003 - AACR
Estrogen receptor (ER) is a ligand-activated transcription factor that mediates estrogen
actions in target tissues. Several common polymorphisms of the ER-α gene have been …

Estrogen and thrombosis: a bench to bedside review

MY Abou-Ismail, DC Sridhar, L Nayak - Thrombosis research, 2020 - Elsevier
Estrogen, in the clinical setting is used primarily for contraception and hormone replacement
therapy. It has been well established that estrogen increases the risk of both arterial and …

Oestrogen receptor β: what it means for patients with breast cancer

V Speirs, PJ Carder, S Lane, D Dodwell… - The lancet …, 2004 - thelancet.com
Oestrogen receptor (ER) α is a well established prognostic marker in breast cancer, and all
patients who are ER α positive receive tamoxifen as adjuvant endocrine therapy. Although …

Evaluation of seven oestrogen receptor β antibodies for immunohistochemistry, western blotting, and flow cytometry in human breast tissue

GP Skliris, AT Parkes, JL Limer… - The Journal of …, 2002 - Wiley Online Library
Two oestrogen receptors, ERα and ERβ, exist. While much is known about ERα, the role of
ERβ is still undefined, especially at the protein level. The aim of this study was to determine …

Oestrogen receptor splice variants in the pathogenesis of disease

SE Taylor, PL Martin-Hirsch, FL Martin - Cancer letters, 2010 - Elsevier
The full-length oestrogen receptor (ER) exists in most vertebrates as two separately
encoded isoforms. ER splice variants represent truncated or otherwise modified versions of …

Association of estrogen receptor β gene polymorphism with bone mineral density

S Ogawa, T Hosoi, M Shiraki, H Orimo, M Emi… - Biochemical and …, 2000 - Elsevier
Chromosomal mapping of the human estrogen receptor β (ERβ) gene by fluorescence in
situ hybridization (FISH) reveals that ERβ is located at human chromosome 14, region q23 …

Effectiveness of selective estrogen receptor modulators in breast cancer therapy: an update

A Das, KJ Lavanya, K Kaur… - Current Medicinal …, 2023 - ingentaconnect.com
Background: Breast cancer is considered to be 2nd most common cancer subtype
investigated worldwide. It is mainly prevalent in postmenopausal women. Estrogen Receptor …