One of the most promising pharmaceutical research areas is developing advanced delivery
systems for controlled and sustained drug release. The drug delivery system (DDS) can be …

Aquaporin-5 (AQP5), belonging to the aquaporins (AQPs) family of transmembrane water
channels, facilitates osmotically driven water flux across biological membranes and the …

Abstract “Nasal hyperreactivity” is a key feature in various phenotypes of upper airway
diseases, whereby reactions of the nasal epithelium to diverse chemical and physical stimuli …

Chlorpheniramine Maleate (CPM), also known as chlorphenamine, is a potent alkylamine
first-generation H1 antihistamine that has been used since the 1950s. CPM is a widely …

Allergic rhinitis (AR) was a chronic airway inflammatory disease. Nasal administration
showed superiorities due to its effective drug absorption. Cetirizine (CTZ) was a common H …

Abstract Altered aquaporin 5 (AQP5) expression in immune cells impacts on key
mechanisms of inflammation and is associated with sepsis survival. Since epigenetic …

Inflammation is a universal response mechanism existing as inter-communicator of
biological systems. Uncontrolled or dysregulated inflammation addresses chronic low-grade …

The prevalence of allergic rhinitis (AR), including symptoms of sneezing, nasal itching,
airflow obstruction, and nasal discharge caused by histamine and immunoglobulin E (IgE) …

Due to the radiosensitivity of the airway epithelium, radiation-induced sinusitis or bronchitis
is not uncommon, and makes mitigation of resulting inflammatory airway diseases a …

The classification of diabetic nephropathy (DN) as a vascular complication of diabetes
makes the possible involvement of histamine, an endogenous amine that is well known for …