Evidence-based clinical use of nanoscale extracellular vesicles in nanomedicine
Recent research has demonstrated that all body fluids assessed contain substantial
amounts of vesicles that range in size from 30 to 1000 nm and that are surrounded by …
amounts of vesicles that range in size from 30 to 1000 nm and that are surrounded by …
The emerging role of extracellular vesicles as biomarkers for urogenital cancers
The knowledge gained from comprehensive profiling projects that aim to define the complex
genomic alterations present within cancers will undoubtedly improve our ability to detect and …
genomic alterations present within cancers will undoubtedly improve our ability to detect and …
Bladder cancer diagnosis and follow-up: the current status and possible role of extracellular vesicles
E Oeyen, L Hoekx, S De Wachter, M Baldewijns… - International journal of …, 2019 - mdpi.com
Diagnostic methods currently used for bladder cancer are cystoscopy and urine cytology.
Cystoscopy is an invasive tool and has low sensitivity for carcinoma in situ. Urine cytology is …
Cystoscopy is an invasive tool and has low sensitivity for carcinoma in situ. Urine cytology is …
Diagnostic and therapeutic potential of exosomes in cancer: the beginning of a new tale?
Exosomes have emerged as one of the main players in intercellular communication. These
small nano‐sized particles have many roles in various physiological pathways in normal …
small nano‐sized particles have many roles in various physiological pathways in normal …
Different EV enrichment methods suitable for clinical settings yield different subpopulations of urinary extracellular vesicles from human samples
F Royo, P Zuñiga-Garcia… - Journal of …, 2016 - Taylor & Francis
Urine sample analysis is irreplaceable as a non-invasive method for disease diagnosis and
follow-up. However, in urine samples, non-degraded protein and RNA may be only found in …
follow-up. However, in urine samples, non-degraded protein and RNA may be only found in …
Urinary extracellular vesicles as source of biomarkers in kidney diseases
A Gámez-Valero, SI Lozano-Ramos, I Bancu… - Frontiers in …, 2015 - frontiersin.org
Most cells physiologically release vesicles as way of intercellular communication. The so-
called Extracellular Vesicles (EVs) include exosomes, ectosomes, and apoptotic bodies …
called Extracellular Vesicles (EVs) include exosomes, ectosomes, and apoptotic bodies …
Urinary exosomes: the potential for biomarker utility, intercellular signaling and therapeutics in urological malignancy
CA Franzen, RH Blackwell, KE Foreman… - The Journal of …, 2016 - auajournals.org
Purpose: Exosomes are small secreted vesicles that contain proteins, mRNA and miRNA
with the potential to alter signaling pathways in recipient cells. While exosome research has …
with the potential to alter signaling pathways in recipient cells. While exosome research has …
Urinary biomarkers in bladder cancer: where do we stand and potential role of extracellular vesicles
MC Oliveira, HR Caires, MJ Oliveira, A Fraga… - Cancers, 2020 - mdpi.com
Extracellular vesicles (EVs) are small membrane vesicles released by all cells and involved
in intercellular communication. Importantly, EVs cargo includes nucleic acids, lipids, and …
in intercellular communication. Importantly, EVs cargo includes nucleic acids, lipids, and …
Methods for extracellular vesicles isolation in a hospital setting
M Sáenz-Cuesta, A Arbelaiz, A Oregi, H Irizar… - Frontiers in …, 2015 - frontiersin.org
The research in extracellular vesicles (EVs) has been rising during the last decade.
However, there is no clear consensus on the most accurate protocol to isolate and analyze …
However, there is no clear consensus on the most accurate protocol to isolate and analyze …
Exosomes: a novel strategy for treatment and prevention of diseases
J Wang, X Sun, J Zhao, Y Yang, X Cai, J Xu… - Frontiers in …, 2017 - frontiersin.org
An “exosome” is a nanoscale membrane vesicle derived from cell endocytosis that functions
as an important intercellular communication mediator regulating the exchange of proteins …
as an important intercellular communication mediator regulating the exchange of proteins …