An initiation-promotion protocol was used to test the hypothesis that unleaded gasoline (UG)
vapor acts as a liver tumor promoter in female mice under exposure conditions in which UG …

Despite the clear net clinical benefit of oral anticoagulation (OAC) in atrial fibrillation (AF)
patients at risk for stroke, major bleeding events (especially intra-cranial bleeds) may be …

Background The use of aspirin in the primary prevention of cardiovascular events remains
controversial. We aimed to assess the efficacy and safety of aspirin versus placebo in …

The task of developing ESC Guidelines covers not only the integration of the most recent
research, but also the creation of educational tools and implementation programmes for the …

The role of low-dose thrombolysis in the reduction of pulmonary artery pressure in moderate
pulmonary embolism (PE) has not been investigated. Because the lungs are very sensitive …

Document Reviewers: Sigmund Silber (CPG Review Coordinator)(Germany), Frank V.
Aguirre (USA), Nawwar Al-Attar (France), Eduardo Alegria (Spain), Felicita Andreotti (Italy) …

The management of acute myocardial infarction continues to undergo major changes. Good
practice should be based on sound evidence derived from well-conducted clinical trials …

Background Studies have reported that women with acute myocardial infarction have in-
hospital and long-term outcomes that are worse than those of men. Methods To assess sex …

Aims There have been no large observational studies attempting to identify predictors of
major bleeding in patients with acute coronary syndromes (ACS), particularly from a …

This article about hemorrhagic complications of anticoagulant and thrombolytic treatment is
part of the Antithrombotic and Thrombolytic Therapy: American College of Chest Physicians …