Association of the tumour necrosis factor α− 308G/A polymorphism with the risk of diabetes in an elderly population-based cohort

BT Heijmans, RGJ Westendorp, S Droog, C Kluft… - Genes & …, 2002 - nature.com
Ample evidence supports a role for tumour necrosis factor α (TNFα) in the development of
type 2 diabetes and cardiovascular disease. TNFα expression was found to be influenced by …

No association between the –308 polymorphism in the tumour necrosis factor α (TNFα) promoter region and polycystic ovaries

CR Milner, JE Craig, ND Hussey… - Molecular human …, 1999 - academic.oup.com
The tumour necrosis factor (TNF) 2 allele appears to be linked with increased insulin
resistance and obesity, conditions often found in overweight patients with polycystic ovary …

Hunting for human obesity genes? Look in the adipose tissue!

P Arner - International Journal of Obesity, 2000 - nature.com
Over-eating and physical inactivity in combination with genetic factors play the most
important roles in the development of over weight in humans. The common genetic …

Tumour necrosis factor-α gene haplotype is associated with pre-eclampsia

T Saarela, M Hiltunen, S Helisalmi… - Molecular human …, 2005 - academic.oup.com
We determined whether polymorphisms in the promoter region of the tumour necrosis factor
alpha (TNF-α) gene contributes to differences in susceptibility to develop pre-eclampsia. The …

Воспаление и факторы риска сердечно-сосудистых заболеваний

НВ Орлова - Москва, 2008 - static.freereferats.ru
Сердечнососудистые заболевания, несмотря на современные технологии диагностики
и лечения, продолжают лидировать по распространенности, инвалидизации и …

Plasma tumor necrosis factor α levels and insulin sensitivity in hypertensive subjects

WHH Sheu, WJ Lee, RL Chang… - Clinical and experimental …, 2000 - Taylor & Francis
Recent studies have shown that tumor necrosis factor-alpha (TNFα), secreted by
macrophage, adipocyte and muscle cells, are associated with insulin resistance syndrome …

Association of interleukin-1β gene polymorphism with body mass index in women

JY Um, HS Chung, MY Song, HD Shin… - Clinical …, 2004 - academic.oup.com
6. Temerinac S, Klippel S, Strunck E, Roder S, Lubbert M, Lange W, et al. Cloning of PRV-1,
a novel member of the uPAR receptor superfamily, which is overexpressed in polycythemia …

Tumor necrosis factor alpha gene G-308A polymorphism, insulin resistance, and fasting plasma glucose in young, older, and diabetic Japanese men

T Ishii, H Hirose, I Saito, K Nishikai… - Metabolism …, 2000 - metabolismjournal.com
In obese subjects, the levels of tumor necrosis factor alpha (TNF-α) expression and protein
synthesis in adipocytes are increased. A recent study of Caucasians suggested that the TNF …

Association between tumour necrosis factor-α G-308A polymorphism and risk of nephropathy in obese Chinese type 2 diabetic patients

Y Wang, MCY Ng, WY So, R Ma, GTC Ko… - Nephrology Dialysis …, 2005 - academic.oup.com
Abstract Background. The G-308A polymorphism in the promoter region of the tumor
necrosis factor alpha (TNF-α) gene has been reported to be associated with insulin …

Tumor necrosis factor‐α regulates secretion of the adipocyte‐derived cytokine, leptin

BN Finck, RW Johnson - Microscopy research and technique, 2000 - Wiley Online Library
The seminal observation that secretion of the adipocyte‐derived hormone leptin was
induced by inflammatory challenge has been expanded upon to demonstrate the …