Obesity leads to chronic, systemic inflammation and can lead to insulin resistance (IR), β-cell
dysfunction, and ultimately type 2 diabetes (T2D). This chronic inflammatory state …

Diabetic sensorimotor peripheral neuropathy (DSPN) is a serious complication of diabetes
mellitus and is associated with increased mortality, lower-limb amputations and distressing …

Aims/hypothesis The term prediabetes is used for individuals who have impaired glucose
metabolism whose glucose or HbA 1c levels are not yet high enough to be diagnosed as …

Background Cluster analyses have proposed different diabetes phenotypes using age, BMI,
glycaemia, homoeostasis model estimates, and islet autoantibodies. We tested whether …

This review takes an inclusive approach to microvascular dysfunction in diabetes mellitus
and cardiometabolic disease. In virtually every organ, dynamic interactions between the …

Peripheral neuropathy is one of the most common complications of both type 1 and type 2
diabetes. Up to half of patients with diabetes develop neuropathy during the course of their …

Vascular complications of diabetes pose a severe threat to human health. Prevention and
treatment protocols based on a single vascular complication are no longer suitable for the …

Diabetic peripheral neuropathy (DPN) is a common chronic complication of diabetes
mellitus. It leads to distressing and expensive clinical sequelae such as foot ulceration, leg …

Abstract Purpose of Review The prevalence of diabetes mellitus and its chronic
complications are increasing to epidemic proportions. This will unfortunately result in …

Diabetic sensorimotor polyneuropathy (DSPN) is encountered in approximately one‐third of
people with diabetes. This, in turn, might markedly impoverish their quality of life, mainly …