Lung cancer—where are we today? Current advances in staging and nonsurgical treatment

SG Spiro, JC Porter - American journal of respiratory and critical …, 2002 - atsjournals.org
Lung cancer remains the commonest cause of cancer death in both men and women in the
developed world, although mortality rates for men are dropping. Spiral computed …

Treatment of stage III non-small cell lung cancer: Diagnosis and management of lung cancer: American College of Chest Physicians evidence-based clinical practice …

N Ramnath, TJ Dilling, LJ Harris, AW Kim, GC Michaud… - Chest, 2013 - Elsevier
Objectives Stage III non-small cell lung cancer (NSCLC) describes a heterogeneous
population with disease presentation ranging from apparently resectable tumors with occult …

The management of patients with stage IIIA non–small cell lung cancer with N2 mediastinal node involvement

RG Martins, TA D'Amico, BW Loo… - Journal of the National …, 2012 - jnccn.org
Patients with stage IIIA non–small cell lung cancer, determined based on involvement of
ipsilateral mediastinal lymph nodes, represent the most challenging management problem …

Preresectional chemotherapy in stage IIIA non-small-cell lung cancer: a 7-year assessment of a randomized controlled trial

R Rosell, J Gómez-Codina, C Camps, JJ Sánchez… - Lung cancer, 1999 - Elsevier
In 1989, we began a multicenter study to evaluate the potential benefit of preoperative
chemotherapy with cisplatin, ifosfamide and mitomycin over surgery alone in CT-visible N2 …

[HTML][HTML] Prognostic factors affecting long-term outcomes in patients with resected stage IIIA pN2 non-small-cell lung cancer: 5-year follow-up of a phase II study

DC Betticher, SF Hsu Schmitz, M Tötsch… - British journal of …, 2006 - nature.com
The aim was to investigate the efficacy of neoadjuvant docetaxel–cisplatin and identify
prognostic factors for outcome in locally advanced stage IIIA (pN2 by mediastinoscopy) non …

[HTML][HTML] A randomized trial comparing induction chemotherapy followed by surgery with surgery alone for patients with stage IIIA N2 non-small cell lung cancer (JCOG …

K Nagai, R Tsuchiya, T Mori, H Tada, Y Ichinose… - The Journal of Thoracic …, 2003 - Elsevier
Objective: We performed a prospective randomized trial in patients with potentially
resectable stage IIIA N2 non-small cell lung cancer to confirm the efficacy of induction …

[HTML][HTML] Pathologic complete response to preoperative chemotherapy predicts cure in early-stage non–small-cell lung cancer: combined analysis of two IFCT …

G Mouillet, E Monnet, B Milleron, M Puyraveau… - Journal of Thoracic …, 2012 - Elsevier
Introduction: Our study aimed to evaluate whether pathologic complete response (pCR) in
early-stage non–small-cell lung cancer (NSCLC) after neoadjuvant chemotherapy resulted …

[HTML][HTML] Improved survival associated with neoadjuvant chemoradiation in patients with clinical stage IIIA (N2) non–small-cell lung cancer

M Koshy, SA Fedewa, R Malik, MK Ferguson… - Journal of Thoracic …, 2013 - Elsevier
Introduction Optimal management of clinical stage IIIA-N2 non–small-cell lung cancer
(NSCLC) is controversial. This study examines whether neoadjuvant chemoradiation plus …

An initial experience with FDG-PET in the imaging of residual disease after induction therapy for lung cancer

T Akhurst, RJ Downey, MS Ginsberg, M Gonen… - The Annals of thoracic …, 2002 - Elsevier
Background. The 2-fluoro-2-deoxy-d-glucose positron emission tomography (FDG-PET)
imaging is an advance over computed tomography alone in the staging of untreated …

[HTML][HTML] Primary mediastinal nonseminomatous germ cell tumors: the influence of postchemotherapy pathology on long-term survival after surgery

KA Kesler, KM Rieger, KN Ganjoo, M Sharma… - The Journal of thoracic …, 1999 - Elsevier
Objectives: The treatment of nonseminomatous germ cell tumors with cisplatin-based
chemotherapy followed by aggressive surgical resection of residual disease is one of the …