[HTML][HTML] Pancreatic cancer: molecular characterization, clonal evolution and cancer stem cells
E Pelosi, G Castelli, U Testa - Biomedicines, 2017 - mdpi.com
Pancreatic Ductal Adenocarcinoma (PDAC) is the fourth most common cause of cancer-
related death and is the most lethal of common malignancies with a five-year survival rate …
related death and is the most lethal of common malignancies with a five-year survival rate …
Reviewing two decades of nanomedicine implementations in targeted treatment and diagnosis of pancreatic cancer: An emphasis on state of art
Pancreatic cancer is nowadays the most life-threatening cancer type worldwide. The
problem of poor diagnosis, anti-neoplastics resistance and biopharmaceutical drawbacks of …
problem of poor diagnosis, anti-neoplastics resistance and biopharmaceutical drawbacks of …
Rising trends in pancreatic cancer incidence and mortality in 2000–2014
Background The morbidity and mortality of pancreatic cancer vary considerably around the
world. The aim of this study was to characterize and evaluate recent changes in incidence …
world. The aim of this study was to characterize and evaluate recent changes in incidence …
Mapping intellectual structure and research performance for the nanoparticles in pancreatic cancer field
X Zhu, Q Kong, X Niu, L Chen, C Ge - International journal of …, 2020 - Taylor & Francis
Objective To comprehensively analyze the global scientific outputs of nanoparticles in
pancreatic cancer research. Methods Publications regarding the nanoparticles in pancreatic …
pancreatic cancer research. Methods Publications regarding the nanoparticles in pancreatic …
[HTML][HTML] Human mesenchymal stem cell-derived exosomal microRNA-143 promotes apoptosis and suppresses cell growth in pancreatic cancer via target gene …
B Wang, Y Xu, Y Wei, L Lv, N Liu, R Lin, X Wang… - Frontiers in …, 2021 - frontiersin.org
Background This study aimed to explore the regulatory mechanism of hsa-miR-143-3p and
lncRNA RP11-363N22. 3–functioning upstream of KRAS–in exosomes derived from human …
lncRNA RP11-363N22. 3–functioning upstream of KRAS–in exosomes derived from human …
[HTML][HTML] microRNA-26a represses pancreatic cancer cell malignant behaviors by targeting E2F7
L Wang, M Li, F Chen - Discover Oncology, 2021 - Springer
Dysregulation of microRNAs (miRNAs) exerts key roles in the development of pancreatic
cancer (PCa). miR-26a is reportedly a tumor suppressor in cancers. However, whether miR …
cancer (PCa). miR-26a is reportedly a tumor suppressor in cancers. However, whether miR …
[HTML][HTML] Development and mechanistic insight into the enhanced cytotoxic potential of parvifloron D albumin nanoparticles in EGFR-overexpressing pancreatic cancer …
Pancreatic cancer is one of the most lethal cancers, with an extremely poor prognosis. The
development of more effective therapies is thus imperative. Natural origin compounds …
development of more effective therapies is thus imperative. Natural origin compounds …
[HTML][HTML] Terphenyllin suppresses orthotopic pancreatic tumor growth and prevents metastasis in mice
J Zhang, W Wang, Y Zhou, J Yang, J Xu, Z Xu… - Frontiers in …, 2020 - frontiersin.org
Pancreatic cancer (PC) is an aggressive and fatal disease with high incidences of
metastasis and recurrence. However, there are no effective treatment options for the majority …
metastasis and recurrence. However, there are no effective treatment options for the majority …
[HTML][HTML] Combination treatment strategy for pancreatic cancer involving the novel HDAC inhibitor MPT0E028 with a MEK inhibitor beyond K-Ras status
MW Chao, LH Chang, HJ Tu, CD Chang, MJ Lai… - Clinical …, 2019 - Springer
Abstract Background Oncogenic K-Ras signaling highly relies on the canonical
Ras/MEK/ERK pathway to contribute to pancreatic cancer progression. However, numerous …
Ras/MEK/ERK pathway to contribute to pancreatic cancer progression. However, numerous …
Deubiquitination of FBP1 by USP7 blocks FBP1–DNMT1 interaction and decreases the sensitivity of pancreatic cancer cells to PARP inhibitors
X Cheng, B Zhang, F Guo, H Wu, X Jin - Molecular Oncology, 2022 - Wiley Online Library
Poly [ADP‐ribose] polymerase (PARP) inhibitors can block DNA single‐strand damage
repair and subsequently increase double‐stranded breaks (DSBs) by reducing the activity of …
repair and subsequently increase double‐stranded breaks (DSBs) by reducing the activity of …